Myasthenia gravis appearing after thymectomy for thymoma
- 作者：Kondo ; Kazuya ; Monden ; Yasumasa
- 关键词：Thymoma ; Myasthenia gravis ; Postoperative ; Thymectomy
- 刊名：European Journal of Cardio-Thoracic Surgery
- 出版年：2005
- 期刊代码：89_10107940
- 类别：med
- 出版时间：July, 2005
- 卷：28
- 期：1
- 页码：22-25
- 文件大小：79.8 K
摘要
Objective: A few thymoma patients without myasthenia gravis (MG) have been observed to develop MG after total removal of the thymoma (postoperative MG). However, the cause of this is not yet known because of the rarity of postoperative MG patients. This study evaluated the clinical characteristics of the 8 postoperative MG patients. Methods: We compiled 1089 thymoma patients treated between 1990 and 1994 in 115 institutes in Japan, and found 8 cases of postoperative MG. Results: Postoperative MG was found in 8 (0.97%) of 827 thymoma patients without preoperative MG. The postoperative MG patients included 1 male and 7 females, with a mean age of 50.5±15.0 years. The thymoma was completely resected in all cases. The surgical method used was extended thymectomy in 2 cases and thymothymectomy in 6 cases. There were 2 cases (0.7%) of postoperative MG in the extended thymectomy group (n