A clinicopathological study of the significance of the proportion of choroid morphology in chordoid meningioma

详细信息	查看全文 | 推荐本文 |

• 作者：Jui-Wei Lin^a ; Cheng-Hsien Lu^b ; Wei-Che Lin^c ; You-Ting Wu^a ; Yu-Jie Huang^d ; Fu-Yuan Shih^e ; Jih-Tsun Ho^e ; Ming-Jung Chuang^e ; ^{dearjimmyc@gmail.com}
• 关键词：Chordoid meningioma ; Meningioma ; Tumor progression
• 刊名：Journal of Clinical Neuroscience
• 出版年：2012
• 期刊代码：165_09675868
• 类别：med
• 出版时间：June, 2012
• 卷：19
• 期：6
• 页码：836-843
• 文件大小：520 K

摘要

Chordoid meningiomas (CM) account for approximately 0.5%to 1.0%of intracranial meningiomas. This tumor has a strong risk of recurrence and aggressive growth (World Health Organization grade II). Histological analysis of CM tumors shows that the tissue is often dominated by chordoid morphology; however, the exact relationship between the percentage of the chordoid component and other clinicopathological features is unknown. We collected 26 surgical specimens from 17 patients who had a histological diagnosis of CM between January 1986 and June 2010. The chordoid elements constituted 30%to 98%of the area of the tumor. In 12 of 17 (70.6%) primary tumors, over 50%of the area displayed the chordoid pattern. Recurrence was noted in nine of these patients and five underwent a second operation. These five patients showed a histopathological progression of aggressive features. The proportion of chordoid elements in each recurrent tumor also increased. Thus, the chordoid proportion in CM is associated with a greater likelihood of recurrence.