The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies

详细信息	查看全文 | 推荐本文 |

• 作者：Asher Ornoy ; Naama Zvi ; Judy Arnon ; Rebecka Wajnberg ; Svetlana Shechtman ; Orna Diav-Citrin
• 关键词：Topiramate ; Pregnancy ; Spontaneous abortions ; Congenital anomalies
• 刊名：Reproductive Toxicology
• 出版年：2008
• 期刊代码：233_08906238
• 类别：med
• 出版时间：April 2008
• 卷：25
• 期：3
• 页码：388-389
• 文件大小：102 K

摘要

In spite of a substantial increase in the use of topiramate at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 52 pregnancies with 41 liveborn infants from which it seems that topiramate reduces birth weight without decreasing gestational age at delivery, but does not seem to increase the risk for structural defects. There was an increased rate of spontaneous abortions not related to the drug effects.