Ultrasonography for Diagnosing Carpal Tunnel Syndrome: A Meta-Analysis of Diagnostic Test Accuracy

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• 作者：Ta-Wei Tai^&lowast ; ; ^&dagger ; ; ^&Dagger ; ; Cheng-Yi Wu^&lowast ; ; ^¶ ; ; Fong-Chin Su^&dagger ; ; ^&Dagger ; ; Tai-Chang Chern^§ ; ; I-Ming Jou^&lowast ; ; ^{jming@mail.ncku.edu.tw}
• 关键词：Carpal tunnel syndrome ; Median nerve ; Cross-sectional area ; Ultrasonography ; Meta-analysis ; Sensitivity ; Specificity ; Diagnostic accuracy
• 刊名：Ultrasound in Medicine and Biology
• 出版年：2012
• 期刊代码：82_03015629
• 类别：ph
• 出版时间：July, 2012
• 卷：38
• 期：7
• 页码：1121-1128
• 文件大小：758 K

摘要

Ultrasonography is widely used to diagnose carpal tunnel syndrome (CTS), a common peripheral neuropathy, but the reported diagnostic accuracy varies. This meta-analysis focused on the diagnostic test accuracy of ultrasonography for diagnosing CTS. Structured searches of PubMed for 1990-2010 were done and the data were extracted and meta-analyzed by pooling estimates of sensitivity, specificity, likelihood ratios and diagnostic odds ratios. Diagnostic performance was also judged by using a summary receiver operating characteristic curve. Twenty-eight trials involving 3995 wrists were included. A greater cross-sectional area (CSA) of the median nerve at the carpal tunnel inlet (CSA-I) and a greater flattening ratio at the level of the hamate were seen in CTS wrists than in control wrists. A CSA-I 鈮? mm² is the best single diagnostic criterion, with a diagnostic odds ratio of 40.4 (sensitivity 87.3%, specificity 83.3%).