The Speed of Sound and Attenuation of an IEC Agar-Based Tissue-Mimicking Material for High Frequency Ultrasound Applications

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• 作者：Chao Sun^&lowast ; ; ^{C.Sun-2@sms.ed.ac.uk} ; Stephen D. Pye^&dagger ; ; Jacinta E. Browne^&Dagger ; ; Anna Janeczko^&dagger ; ; Bill Ellis^&dagger ; ; Mairead B. Butler^&lowast ; ; Vassilis Sboros^&lowast ; ; Adrian J.W. Thomson^&lowast ; ; Mark P. Brewin^§ ; ; Charles H. Earnshaw^|| ; Carmel M. Moran^&lowast ;
• 关键词：Ultrasound ; High frequency ; Tissue mimicking material ; Speed of sound ; Attenuation ; Frequency dependence
• 刊名：Ultrasound in Medicine and Biology
• 出版年：2012
• 期刊代码：82_03015629
• 类别：ph
• 出版时间：July, 2012
• 卷：38
• 期：7
• 页码：1262-1270
• 文件大小：539 K

摘要

This study characterized the acoustic properties of an International Electromechanical Commission (IEC) agar-based tissue mimicking material (TMM) at ultrasound frequencies in the range 10-47 MHz. A broadband reflection substitution technique was employed using two independent systems at 21掳C聽卤聽1掳C. Using a commercially available preclinical ultrasound scanner and a scanning acoustic macroscope, the measured speeds of sound were 1547.4聽卤聽1.4 m鈭檚^鈭? and 1548.0聽卤聽6.1 m鈭檚^鈭?, respectively, and were approximately constant over the frequency range. The measured attenuation (dB鈭檆m^鈭?) was found to vary with frequency f (MHz) as 0.40f聽+聽0.0076f². Using this polynomial equation and extrapolating to lower frequencies give values comparable to those published at lower frequencies and can estimate the attenuation of this TMM in the frequency range up to 47 MHz. This characterisation enhances understanding in the use of this TMM as a tissue equivalent material for high frequency ultrasound applications.