Simple scale-up of recombinant antibody production using an UCOE containing vector

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• 作者：Sabrina Boscolo¹ ; Francesca Mion¹ ; ² ; Marta Licciulli¹ ; Paolo Macor¹ ; Luca De Maso¹ ; Martina Brce¹ ; Michael N. Antoniou³ ; Roberto Marzari¹ ; Claudio Santoro⁴ ; Daniele Sblattero⁴ ; ^{sblatter@med.unipmn.it} ; ^{daniele.sblattero@med.unipmn.it}
• 刊名：New Biotechnology
• 出版年：2012
• 期刊代码：P59_18716784
• 类别：imm
• 出版时间：15 May, 2012
• 卷：29
• 期：4
• 页码：477-484
• 文件大小：790 K

摘要

Recombinant proteins, in particular antibodies, have become fundamental in biomedical research where they are used in numerous therapeutic and diagnostic applications. For this reason there is an increasing demand for quick and economical production systems for recombinant proteins in mammalian cells.