Splenic lesions in Hodgkin's and non-Hodgkin's lymphomas. An ultrasonographic study
- 作者：Di Stasi ; M. ; Cavanna ; L. ; Fornari ; F. ; Vallisa ; D. ; Buscarini ; E. ; Civardi ; G. ; Rossi ; S. ; Bertè ; R. ; et. al.
- 关键词：Ultrasound study ; Malignant lymphoma ; Spleen neoplasm ; Hodgkin's disease ; Non-Hodgkin's disease
- 刊名：European Journal of Ultrasound
- 出版年：1995
- 期刊代码：20_09298266
- 类别：ph
- 出版时间：April, 1995
- 卷：2
- 期：2
- 页码：117-124
- 文件大小：760 K
摘要
Objective: To reassess, in patients with lymphoma, the prevalence of splenic involvement by the disease, the ultrasound findings and the correlations with the histological data. Methods: A total of 342 consecutive patients, 56 with Hodgkin's (HL) and 286 with non-Hodgkin's lymphoma (NHL), were submitted to abdominal ultrasonography (US). The US-detected lymphomatous lesions were divided into: (1) small (less than 1 cm) and diffuse, producing a pattern of parenchymal infiltration; (2) focal. In the latter, the US patterns and the number and size of the lesions were registered. The lymphomatous nature of the splenic lesions was proved pathologically or by follow-up. Results: Fifty-four of the 342 patients showed splenic lesions; there were patients with HL (16.1%) and with NHL (15.7%); most of the lesions occurred at the initial staging and advanced stages of the diseases. Lesions of the diffuse type were found in 33%of the patients, both in HL and NHL; 67%of the patients had nodular lesions. Of the 54 spleens involved, 14 (26%) were normal-sized. In NHLs, the diffuse type lesions occurred mostly in low/intermediate grade and the nodular type in intermediate/high grade diseases. In total, 50%of all the nodular lesions were single and 50%were larger than 3 cm. In 67%of cases for HL and in 73%for NHL, the lesions were hypoechoic. Conclusions: US may reliably detect splenic involvement from lymphoma only if a modification of echo-texture is produced, as the size of the spleen is an insufficient criterion. The overall prevalence of splenic lesions in our series was 15.8%; it was higher than those previously reported. Lymphomatous lesions were confirmed to be mostly hypoechoic; only the correlations between diffuse lesions and low/intermediate grade NHLs and between nodular lesions and intermediate/high grade NHLs were confirmed.