Mitral annular longitudinal function preservation after mitral valve repair: The MARTE study

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• 作者：M. Lisi^a ; ^{matteo.lisi@hotmail.it} ; P. Ballo^b ; M. Cameli^a ; F. Gandolfo^c ; M. Galderisi^d ; M. Chiavarelli^c ; M.Y. Henein^e ; S. Mondillo^a
• 关键词：Longitudinal function ; Mitral valve
• 刊名：International Journal of Cardiology
• 出版年：2012
• 期刊代码：128_01675273
• 类别：med
• 出版时间：31 May, 2012
• 卷：157
• 期：2
• 页码：212-215
• 文件大小：449 K

摘要

Background

In patients with chronic mitral regurgitation (MR), undergoing surgical mitral valve repair, current Guidelines only recommend standard echocardiographic indices i.e. left ventricular (LV) ejection fraction (EF), and LV end-systolic and end-diastolic diameters as preoperative variables. However LV EF is often preserved until advanced stages of the valve disease. Aim of this study was to evaluate changes in LV systolic longitudinal function, 3 months after mitral valve repair in patients with chronic degenerative MR and normal preoperative EF.

Methods

We measured M-mode mitral lateral annulus systolic excursion (MAPSE) and Tissue Doppler (TD) peak systolic annular velocity (S_m) in 31 patients with moderate to severe MR and normal EF (59.9 卤 4.7%) candidates for mitral valve repair, preoperatively and 3 months after surgery.

Results

After mitral valve repair, S_m increased from 7.8 卤 1.4 to 9.6 卤 2.2 cm/s (p < 0.0001) and MAPSE increased from 1.33 卤 0.26 to 1.55 卤 0.25 cm (p = 0.0013). EF decreased from 59.9 卤 4.7 to 51.3 卤 5.9%(p < 0.0001). As expected, LV diameters and volumes, wall thicknesses, midwall fractional shortening (mFS), and left atrial (LA) size were all reduced after surgery.

Conclusions

This study suggests that assessment of LV long axis systolic velocity and amplitude of excursion by echocardiography is more sensitive than simple determination of EF for revealing the beneficial impact of MR surgery on overall systolic function.