Tenascin-C expression in invasion border of early breast cancer - A predictor of local and distant recurrence
- 作者：Jahkola ; Tina ; Toivonen ; Terttu ; Virtanen ; Ismo ; von Smitten ; Karl ; Nordling ; Stig ; von Boguslawski ; Kristina ; et. al.
- 刊名：European Journal of Cancer
- 出版年：1998
- 期刊代码：88_09598049
- 类别：med
- 出版时间：September 30, 1998
- 卷：34
- 期：Supplement 5
- 页码：S101
- 文件大小：118 K
摘要
Purpose: Tenascin-C (Tn-C) is an extracellular matrix glycoprotein expressed transiently in areas of epithelial-mesenchymal interaction during embryogenesis and neoplasia. Our previous work showed an association between metastasis and Tn-C expressed in invasion border of axillary node-negative breast carcinomas. Our aim was to relate this Tn-C expression with several histopathological and biological variables and to compare their usefulness to predict recurrences.