Carotid arterial stiffness is marginally higher in the metabolic syndrome and markedly higher in type 2 diabetes mellitus in patients with manifestations of arterial disease

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• 作者：Fabrice M.A.C. Martens ; Yol ; a van der Graaf ; Joke M. Dijk ; Jobien K. Olijhoek ; Frank L.J. Visseren
• 关键词：Carotid artery stiffness ; Diabetes mellitus ; Metabolic syndrome
• 刊名：Atherosclerosis
• 出版年：2008
• 期刊代码：28_00219150
• 类别：med
• 出版时间：April 2008
• 卷：197
• 期：2
• 页码：646-653
• 文件大小：131 K

摘要

Insulin resistance is generally considered to be of major importance in the pathophysiology of the metabolic syndrome and type 2 diabetes mellitus, both high-risk conditions for cardiovascular complications. Carotid artery stiffness is increasingly recognized as an important predictor of cardiovascular morbidity and mortality. Therefore, in the present study we determined whether the metabolic syndrome (MetSyn) and type 2 diabetes mellitus (DM2) are associated with carotid artery stiffness in patients with already clinical manifestations of arterial disease.