Inhibitory control after traumatic brain injury in children

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• 作者：Katia J. Sinopoli^a ; ^c ; ^d ; ^{katia.sinopoli@sickkids.ca} ; Maureen Dennis^b ; ^d ; ^e
• 关键词：TBI ; Inhibitory control ; Effortful inhibition ; Effortless inhibition
• 刊名：International Journal of Developmental Neuroscience
• 出版年：2012
• 期刊代码：28_07365748
• 类别：neu
• 出版时间：May, 2012
• 卷：30
• 期：3
• 页码：207-215
• 文件大小：501 K

摘要

Inhibitory control describes a number of distinct processes. Effortless inhibition refers to acts of control that are automatic and reflexive. Effortful inhibition refers to voluntary, goal-directed acts of control such as response flexibility, interference control, cancellation inhibition, and restraint inhibition. Disruptions to a number of inhibitory control processes occur as a consequence of childhood traumatic brain injury (TBI). This paper reviews the current knowledge of inhibition deficits following childhood TBI, and includes an overview of the inhibition construct and a discussion of the specific deficits shown by children and adolescents with TBI and the factors that mediate the expression of these deficits, including injury-related variables and the expression of pre- and post-injury attention-deficit/hyperactivity disorder. The review illustrates that inhibitory control processes differ in terms of measurement, assessment, and neurological underpinnings, and also that childhood TBI may selectively disrupt particular forms of inhibition.