Comparison of anterior ocular biometry between optical low-coherence reflectometry and anterior segment optical coherence tomography in an adult Chinese population
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摘要
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Purpose

To evaluate the agreement between optical low-coherence reflectometry (OLCR) and anterior segment optical coherence tomography (AS-OCT) for biometry of the anterior segment.

Setting

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Design

Evaluation of diagnostic technology.

Methods

A series of OLCR (Lenstar LS 900) and AS-OCT measurements of the anterior segment were taken for consecutive subjects aged 35 years and older in a population-based study. The differences and correlations between the 2 methods of ocular biometry were assessed. Agreement was calculated as the 95%limits of agreement (LoA).

Results

The mean age of the 776 subjects was 55.2 years 卤 12.0 (SD); 54.6%were women. The聽mean central corneal thickness (CCT) was smaller with OLCR than with AS-OCT (537.84 卤 31.46 渭m versus 559.39 卤 32.02 渭m) as was anterior chamber depth (ACD) (2.60 卤 0.37 mm versus 2.72 卤 0.37 mm) and anterior chamber width (ACW) (11.76 卤 0.47 mm versus 12.04聽卤 0.55 mm) (all P<.001). The 95%LoA between the 2 instruments were 鈭?4.80 to 1.71聽渭m for CCT, 鈭?.17 to 鈭?.06 mm for ACD, and 鈭?.28 to 0.72 mm for ACW.

Conclusion

Optical low-coherence reflectometry and AS-OCT yielded potentially interchangeable ACD measurements, while the CCT and ACW measurements acquired by the 2 devices showed clinically significant differences.

Financial Disclosure

No author has a financial or proprietary interest in any material or method mentioned.

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