Selective oxidation of benzylic or allylic hydroxyl group of sec-1,2-diols

详细信息	查看全文 | 推荐本文 |

• 作者：Peng ; Kun ; Chen ; Fuxin ; She ; Xuegong ; Yang ; Chunhui ; Cui ; Yuxin ; Pan ; Xinfu
• 关键词：Selective oxidation ; DDQ ; Ultrasound wave ; Vicinal position
• 刊名：Tetrahedron Letters
• 出版年：2005
• 期刊代码：109_00404039
• 类别：ch
• 出版时间：February 14, 2005
• 卷：46
• 期：7
• 页码：1217-1220
• 文件大小：104 K

摘要

A mild and efficient method to selectively oxidize chiral sec-1,2-diols has been developed, which demonstrates that 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) can selectively oxidize benzylic or allylic hydroxyl group of sec-1,2-diols under ultrasound wave promotion. The configuration of the adjacent chiral center is retained.