An efficient method for direct aldol reactions catalyzed by pyrrolidine/catechol: The influence of cooperation of Brønsted acidity and hydrogen-bond on the reaction
- 作者：Changyun Ji ; Yungui Peng ; Chengzhi Huang ; Ning Wang ; Zhen Luo and Yaozhong Jiang
- 关键词：Aldol reaction ; Pyrrolidine ; Catechol ; Bifunctional catalysis
- 刊名：Journal of Molecular Catalysis A ; Chemical
- 出版年：2006
- 期刊代码：57_13811169
- 类别：ch
- 出版时间：1 March 2006
- 卷：246
- 期：1-2
- 页码：136-139
- 文件大小：134 K
摘要
The aldol reactions of aromatic aldehydes with ketones catalyzed by pyrrolidine were accelerated by addition of a series of Brønsted acids to the reaction medium and found that the catechol was the most effective co-catalyst. The combination of pyrrolidine and catechol are very efficient for catalyzing the reaction to proceeding under mild conditions with high yield in short time.