Effect of polymorphisms of endothelial nitric oxide synthase on ischemic stroke: A case-control study in a Chinese population
- 作者：Jinquan Cheng ; Jianping Liu ; Xiaoxia Li ; Lei Yu ; Ji Peng ; Renli Zhang ; Yijie Geng ; Shaofa Nie
- 关键词：Endothelial nitric oxide synthase ; Polymorphisms ; Ischemic stroke ; Case-control study
- 刊名：Clinica Chimica Acta
- 出版年：2008
- 期刊代码：54_00098981
- 类别：med
- 出版时间：June 2008
- 卷：392
- 期：1-2
- 页码：46-51
- 文件大小：156 K
摘要
Nitric oxide (NO) synthesized by endothelial nitric oxide synthase (eNOS) plays a key role in vascular regulation and atherosclerosis, therefore, eNOS may be a candidate gene for ischemic stroke (IS). However, it is still controversial whether eNOS polymorphisms are a risk factor for IS.