Annual abdominal ultrasonographic examination after curative NSCLC resection

详细信息	查看全文 | 推荐本文 |

• 作者：Keiju Aokage ; Junji Yoshida ; Mitsuyo Nishimura ; Yutaka Nishiwaki ; Kanji Nagai
• 关键词：Ultrasound ; Non-small cell lung cancer ; Postoperative care ; Ultrasonography ; Follow-up ; Recurrence
• 刊名：Lung Cancer
• 出版年：2007
• 期刊代码：187_01695002
• 类别：med
• 出版时间：September 2007
• 卷：57
• 期：3
• 页码：334-338
• 文件大小：230 K

摘要

There is no established follow-up strategy in non-small cell lung cancer patients after complete resection. Follow-up regimens are different between nations, institutions, and surgeons. We tried to investigate the role of annual abdominal ultrasonographic examination in completely resected NSCLC patients.

Methods

We reviewed 265 consecutive patients who had their NSCLC completely resected at our institution from July 1992 through December 2000 and were followed by a single surgeon. Annual abdominal ultrasonography was performed until 5 years after resection. Chest CT and abdominal CT are not included in our routine follow-up program. Instead, we used ultrasonography to survey the abdomen because abdominal ultrasonography is less costly than abdominal CT, is non-invasive, and does not require contrast media.

Results

A total of 892 ultrasonographic examinations were performed. Fifty-nine (22.3%) patients developed recurrence. Annual ultrasonography detected lesions suspicious of recurrence in 15 patients. Further work-up diagnosed NSCLC recurrence in 2 (0.8%) patients (multiple liver metastases in one and right adrenal metastasis in one). The two patients soon developed disseminated disease and died in less than a year.

Conclusions

Annual abdominal ultrasonography in the follow-up protocol for completely resected NSCLC patients was not beneficial. Our experience in the present study may be used as valid evidence to exclude abdominal ultrasonography from future trials comparing follow-up regimens after complete resection of NSCLC. A better follow-up strategy needs to be established.