A fiber-based single-unit dual-mode optical Imaging system: Swept source optical coherence tomography and fluorescence spectroscopy

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• 作者：Seon Young Ryu^a ; Hae Young Choi^b ; Ki Soo Chang^a ; Geon Hee Kim^a ; Woo June Choi^c ; Sang-Gun Ahn^d ; Yong Chul Kim^e ; Jung-Hoon Yoon^f ; ^{opathjhyoon@naver.com} ; Byeong Ha Lee^c ; ^{leebh@gist.ac.kr}
• 关键词：Double-clad fiber coupler ; Optical coherence tomography ; Fluorescence spectroscopy
• 刊名：Optics Communications
• 出版年：2012
• 期刊代码：50_00304018
• 类别：ph
• 出版时间：1 May, 2012
• 卷：285
• 期：9
• 页码：2478-2482
• 文件大小：870 K

摘要

We propose a fiber optic single-unit but dual-mode optical imaging system that can provide fast cross-sectional imaging capabilities of swept-source optical coherence tomography (SS-OCT) and functional capabilities of fluorescence spectroscopy (FS). By adopting a fiber optic FS system into a fiber-based SS-OCT system, a compact and effective multimodal single-unit SSOCT-FS system is achieved. Here, the key element of the proposed multimodal imaging system is a specially designed fiber coupler based on double-clad fiber (DCF), which has only cladding-mode coupling capability. The DCF couplers are fabricated with home-drawn DCF by several fabrication methods; a twisting method, a side-polishing method and a fused biconical tapered (FBT) method. Experimentally, the FBT method provides rather flat cladding mode coupling efficiency over 40%in a wide wavelength range. With this specially designed DCF coupler, the OCT signal and the fluorescence signal is measured independently but with a single-unit system. The performance of the SSOCT-FS system is confirmed by measuring the cross-sectional image and the fluorescence signal of a photosensitizer chlorin e6 injected in-vivo rat tumor model.