Carcinogenic polycyclic aromatic hydrocarbons in umbilical cord blood of human neonates from Guiyu, China

详细信息	查看全文 | 推荐本文 |

• 作者：Yongyong Guo^a ; ¹ ; Xia Huo^a ; ¹ ; Kusheng Wu^a ; ^b ; Junxiao Liu^a ; Yuling Zhang^a ; Xijin Xu^a ; ^c ; ^{xuxj@stu.edu.cn}
• 关键词：Ah ; Aryl hydrocarbon ; BaA ; Benzo[a]anthracene ; BaP ; Benzo[a]pyrene ; BbF ; Benzo[b]fluoranthene ; BbkF ; Benzo[b  ; +  ; k]fluoranthene ; BkF ; Benzo[k]fluoranthene ; Chr ; Chrysene ; DahA ; Dibenz[a ; h]anthracene ; e-waste ; Electronic waste ; GC/MS ; Gas chromatog
• 刊名：Science of the Total Environment
• 出版年：2012
• 期刊代码：63_00489697
• 类别：env
• 出版时间：15 June, 2012
• 卷：427-428
• 期：Complete
• 页码：35-40
• 文件大小：194 K

摘要

Unregulated electronic-waste recycling results in serious environmental pollution of polycyclic aromatic hydrocarbons (PAHs) in Guiyu, China. We evaluated the body burden of seven carcinogenic PAHs and potential health risks for neonates. Umbilical cord blood (UCB) samples were collected from Guiyu (n = 103), and the control area of Chaonan (n = 80), China. PAHs in UCB were determined by gas chromatography/mass spectrometry. The median 鈭?#xA0;7c-PAH concentration was 108.05 ppb in UCB samples from Guiyu, vs. 79.36 ppb in samples from Chaonan. Residence in Guiyu and longer cooking time of food during the gestation period were significant factors contributing to the 鈭?#xA0;7c-PAH level. Benzo[a]anthracene (BaA), chrysene (Chr), and benzo[a]pyrene (BaP) were found to correlate with reduced neonatal height and gestational age. Infants experiencing adverse birth outcomes, on the whole, displayed higher BaA, Chr, and BaP levels compared to those with normal outcomes. We conclude that maternal PAH exposure results in fetal accumulation of toxic PAHs, and that such prenatal exposure correlates with adverse effects on neonatal health.