Dopamine agonist therapy for Parkinson disease and pathological gambling
- 作者：Akiko Imamura ; Ryan J. Uitti ; Zbigniew K. Wszolek
- 关键词：Dopamine agonist ; Levodopa ; Parkinson disease ; Pathological gambling
- 刊名：Parkinsonism and Related Disorders
- 出版年：2006
- 期刊代码：215_13538020
- 类别：med
- 出版时间：December 2006
- 卷：12
- 期：8
- 页码：506-508
- 文件大小：84 K
摘要
We report 6 patients with pathological gambling during pharmacologic treatment for Parkinson disease (PD). Four patients were treated with levodopa/carbidopa and dopamine agonist (DA), and 2 patients received DA monotherapy. We reviewed several published reports regarding pathological gambling and antiparkinsonian therapy and suggest that more advanced PD and antiparkinsonian combination therapy (e.g., levodopa/carbidopa and DA) increases the risk for development of pathological gambling behavior compared with monotherapy with either DA or levodopa/carbidopa.