Oldhamine A, a novel alkaloid from Daphniphyllum oldhami
- 作者：Chengjian Tan ; Yingtong Di ; Yuehu Wang ; Ye Wang ; Shuzhen Mu ; Suo Gao ; Yu Zhang ; Ningchuan Kong ; Hongping He ; Jianxin Zhang ; Xin Fang ; Chunshun Li ; Yang Lu ; Xiaojiang Hao
- 关键词：Daphniphyllaceae ; Daphniphyllum oldhami ; Oldhamine A ; Internal salt ; Cyclopentadienyl anion ; Nortriterpenoid alkaloid
- 刊名：Tetrahedron Letters
- 出版年：2008
- 期刊代码：109_00404039
- 类别：ch
- 出版时间：19 May 2008
- 卷：49
- 期：21
- 页码：3376-3379
- 文件大小：225 K
摘要
Oldhamine A, a novel alkaloid with an unusual cyclopentadienyl anion in the fused-pentacyclic skeleton was isolated from the twigs of Daphniphyllum oldhami. The structure of oldhamine A was elucidated based on the spectroscopic data and the single-crystal X-ray diffraction crystallography. It is the first X-ray diffraction of the Daphniphyllum alkaloids with nitrogen-containing two pentacyclic rings. The inter-conversion between cyclopentadienyl anion and conjugated enolic unit was also conducted.