In situ studies on the distribution patterns and dynamics of microcystins in a biomanipulation fish – bighead carp (Aristichthys nobilis)
- 作者：Jun Chen ; Ping Xie ; Dawen Zhang ; Hehua Lei
- 关键词：Microcystin accumulation ; Bighead carp ; Organs ; Seasonal dynamics ; MC-LR-Cys ; TDI ; Lake Taihu
- 刊名：Environmental Pollution
- 出版年：2007
- 期刊代码：28_02697491
- 类别：env
- 出版时间：May 2007
- 卷：147
- 期：1
- 页码：150-157
- 文件大小：375 K
摘要
The distribution and dynamics of microcystins in various organs of the phytoplanktivorous bighead carp were studied monthly in Lake Taihu, which is dominated by toxic cyanobacteria. There was a good agreement between LC-MS and HPLC-UV determinations. Average recoveries of spiked fish samples were 63%for MC-RR and 71%for MC-LR. The highest MC contents in intestine, liver, kidney and spleen were 85.67, 2.83, 1.70 and 1.57 μg g−1 DW, respectively. MCs were much higher in mid-gut walls (1.22 μg g−1 DW) than in hind- and fore-gut walls (0.31 and 0.18 μg g−1 DW, respectively), suggesting the importance of mid-gut wall as major site for MC absorption. A cysteine conjugate of MC-LR was detected frequently in kidney. Among the muscle samples analyzed, 25%were above the provisional tolerable daily intake level by WHO. Bighead is strongly resistant to microcystins and can be used as biomanipulation fish to counteract cyanotoxin contamination in eutrophic waters.