Room-temperature catalytic hydrodefluorination of pentafluoro-pyridine by zirconocene fluoro complexes and diisobutylaluminumhydride

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• 作者：Ulrike Jä ; ger-Fiedler ; Marcus Klahn ; Perdita Arndt ; Wolfgang Baumann ; Anke Spannenberg ; Vladimir V. Burlakov ; Uwe Rosenthal
• 关键词：Zirconocene ; CF bond activation ; CH bond activation ; Organometallics ; Heterocycles
• 刊名：Journal of Molecular Catalysis A ; Chemical
• 出版年：2007
• 期刊代码：57_13811169
• 类别：ch
• 出版时间：18 January 2007
• 卷：261
• 期：2
• 页码：184-189
• 文件大小：325 K

摘要

Mixtures consisting of zirconocene difluorides Cp^′₂ZrF₂ (Cp′ = substituted or nonsubstituted η⁵-cyclopentadienyl) as pre-catalysts and diisobutylaluminumhydride i-Bu₂AlH as activator were found to be active catalysts in the room-temperature hydrodefluorination (HDF) of fluorinated pyridines. Evaluation of these systems established rac-(ebthi)ZrF₂ (1) and Cp₂ZrF₂ (3) together with i-Bu₂AlH as active catalysts in the room-temperature hydrodefluorination (HDF) of pentafluoro-pyridine. The active species for the conversion were the actually formed hydrides [rac-(ebthi)ZrH(μ-H)]₂ (2) and [Cp₂ZrH(μ-H)]₂ (4). The results we obtained (rt, 24 h, turn over number 67) showed a significantly better performance compared to other investigations published before for this HDF reaction.