伪-Amino acid behaves differently from 尾- or 纬-amino acids as treated by trimetaphosphate
| 详细信息 | 推荐本文 | |
- 作者：X. Gao ; Y. Liu ; P. X. Xu ; Y. M. Cai and Y. F. Zhao
- 关键词：Keywords ; Trimetaphosphate – ; α ; Amino acids – ; β ; Amino acids – ; γ ; Amino acids – ; Peptide – ; LC ; ESI ; MS
- 刊名：Amino Acids
- 出版时间：January, 2008
- 出版年：2008
- 期刊代码：7_0939-4451
- 类别：bio
- 卷：34
- 期：1
- 页码：47-53
- 数据来源：sp
摘要
The condensation reactions of sodium trimetaphosphate with single amino acids, namely glycine, L-alanine, β-alanine and γ-aminobutyric acid or pairs of these amino acids were reinvestigated by electrospray ion-trap mass spectrometry and high performance liquid chromatography. It was found when mixtures were treated by sodium trimetaphosphate only in the presence of α-amino acid dipeptides were formed. Without addition of α-amino acids, the β-amino acid or γ-aminobutyric acid could not form peptide either by themselves or with their mixtures under the same conditions. From the data it is concluded that phosphate might select α-amino acids to produce the peptides being important precursors for the origin of life.