On pseudo-values for regression analysis in competing risks models
| 详细信息 | 推荐本文 | |
- 作者：Frederik Graw ; Thomas A. Gerds and Martin Schumacher
- 关键词：Competing risks ; Generalized estimating equation ; Jackknife pseudo ; values ; Regression models ; Survival analysis ; Von Mises expansion
- 刊名：Lifetime Data Analysis
- 出版时间：June, 2009
- 出版年：2009
- 期刊代码：97_1380-7870
- 类别：mat
- 卷：15
- 期：2
- 页码：241-255
- 数据来源：sp
摘要
For regression on state and transition probabilities in multi-state models Andersen et al. (Biometrika 90:15–27, 2003) propose a technique based on jackknife pseudo-values. In this article we analyze the pseudo-values suggested for competing risks models and prove some conjectures regarding their asymptotics (Klein and Andersen, Biometrics 61:223–229, 2005). The key is a second order von Mises expansion of the Aalen-Johansen estimator which yields an appropriate representation of the pseudo-values. The method is illustrated with data from a clinical study on total joint replacement. In the application we consider for comparison the estimates obtained with the Fine and Gray approach (J Am Stat Assoc 94:496–509, 1999) and also time-dependent solutions of pseudo-value regression equations.