Bone Density in an Immigrant Population from Southeast Asia
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- 作者：M. A. Marquez ; L. J. Melton ; III ; J. M. Muhs ; C. S. Crowson ; A. Tosomeen ; M. K. O鈥機onnor ; W. M. O鈥橣allon and B. L. Riggs
- 关键词：Key words ; Aging – ; Bone mineral density – ; Epidemiology – ; Ethnic group – ; Osteoporosis – ; Southeast Asians
- 刊名：Osteoporosis International
- 出版时间：August 2001
- 出版年：2001
- 期刊代码：176_0937-941X
- 类别：med
- 卷：12
- 期：7
- 页码：595-604
- 数据来源：sp
摘要
The epidemiology of bone loss in populations of Asian heritage is still poorly known. This study compared the skeletal status of a convenience sample of 396 Southeast Asian immigrants (172 Vietnamese, 171 Cambodians and 53 Laotians) residing in Rochester, Minnesota in 1997 with 684 white subjects previously recruited from an age-stratified random sample of community residents. Areal bone mineral density (BMD, g/cm2) and volumetric bone mineral apparent density (BMAD, g/cm3) were determined for lumbar spine and proximal femur using the Hologic QDR 2000 instrument for the white population and the QDR 4500 for Southeast Asian subjects; the machines were cross-calibrated from data on 20 volunteers. Lumbar spine BMD was 7%higher in white than Southeast Asian women ( p < 0.001), and similar results were observed for the femoral neck; lumbar spine BMD was 12%higher in white than nonwhite men ( p < 0.001). Race-specific discrepancies were reduced by calculating BMAD: for premenopausal women, lumbar spine and femoral neck differences between whites and Southeast Asians were eliminated; for postmenopausal women the lumbar spine differences persisted ( p < 0.0001), while femoral neck BMAD was actually higher for Southeast Asians. There were no race-specific differences in femoral neck BMAD among men of any age ( p= 0.312), but lumbar spine BMAD was less for younger ( p= 0.042) but not older ( p= 0.693) Southeast Asian men. There were differences among the Southeast Asian subgroups, but no clear pattern emerged. Predictors of lumbar spine BMAD in Southeast Asian women were age ( p < 0.001), weight ( p= 0.015) and gravidity ( p= 0.037). Even after adjusting for bone size using BMAD, 32%and 9%of Southeast Asian women and men, respectively, would be considered to have osteoporosis at the femoral neck and 25%and 4%, respectively, at the lumbar spine. These findings indicate a need for culturally sensitive educational interventions for Southeast Asians and for physicians to pursue diagnosis and treatment to prevent osteoporosis-related disabilities in this population.