General structural features of centric and acentric polymorphic pairs of organic molecular crystals: II. Polymorphic pairs P21/c-P21, P21/c-Pc, and P21/c-Pna21
摘要
A systematic investigation into the general structural features of centric and acentric polymorphic pairs of organic molecular crystals is performed using the data available in the Cambridge Structural Database. The structural aspects of the P21/c-P21, P21/c-Pc, and P21/c-Pna21 polymorphic pairs are considered. The most important inferences made in this study are as follows: (i) the centric and acentric modifications rather frequently (∼50%of all the cases) crystallize simultaneously under the same conditions (concomitant polymorphism); (ii) the unit cell parameters of these modifications are found to be either close in magnitude or multiples; (iii) in the centric and acentric modifications, identical or very similar types of chiral or acentric stable molecular associates are formed through hydrogen bonds or other specific intermolecular interactions; and (iv) the centric and acentric modifications more often than other compounds are characterized by polysystem unit cells (Z′ > 1).