Synthesis and antimicrobial activity of 2,6-dimethyl-3,5-dialkoxycarbonyl-4-phenyl- 1,4-dihydropyridines
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- 作者：V. L. Gein (1) geinvl48@mail.ru
M. I. Kazantseva (1)
A. A. Kurbatova (1)
E. V. Voronina (1) - 关键词：Key words Hantzsch synthesis – ; 2 ; 6 ; dimethyl ; 3 ; 5 ; dialkoxycarbonyl ; 4 ; phenyl ; 1 ; 4 ; dihydropyridines – ; antimicrobial activity
- 刊名：Pharmaceutical Chemistry Journal
- 出版时间：October 2011
- 出版年：2011
- 期刊代码：30_0091150X
- 类别：en
- 卷：45
- 期：8
- 页码：474-475
- 数据来源：sp
摘要
Reaction of acetoacetic esters, aromatic aldehydes, and ammonia formed under Hantzsch conditions 2,6-dimethyl-3,5-dialkoxycarbonyl-1,4-dihydropyridines. The structures of the products were established using mass, IR, and PMR spectra. It was found that all synthesized compounds exhibited moderate antimicrobial activity.