Adenomyoepithelioma of the breast diagnosed by a mammotome biopsy: Report of a case
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- 作者：Toshiro Yahara ; Rin Yamaguchi ; Goro Yokoyama ; Miki Yamaguchi ; Shino Nakagawa ; Uhi Toh ; Kazuo Shirouzu ; Masayoshi Kage and Teruhiko Fujii
- 关键词：Adenomyoepithelioma ; Breast ; Mammotome biopsy
- 刊名：Surgery Today
- 出版时间：February, 2008
- 出版年：2008
- 期刊代码：206_0941-1291
- 类别：med
- 卷：38
- 期：2
- 页码：144-146
- 数据来源：sp
摘要
Adenomyoepithelioma is an uncommon primary breast tumor. It is conspicuous for two elements of the tumor, namely, ductal and myoepithelial components. Recently, a Mammotome biopsy, or stereotactic vacuum-assisted biopsy has become popular and various benign or borderline lesions are obtained. We report an adenomyoepithelioma of the breast in a 56-year-old woman. She was pointed out to have a cluster of some microcalcifications on mammography and a 9-mm hypoechoic mass lesion was detected by ultrasound. A Mammotome biopsy revealed a well-defined lesion. Histologically, the tumor demonstrated a thick and bi-cellular growth pattern consisting of ducts and myoepithelium. Immunohistochemically, epithelial cells were positive for cytokeratin AE1/AE3 and cytokeratin, epithelial membrane antigen (EMA), and carcinoembryonic antigen (CEA), negative for alpha-smooth muscle actin (alpha-SMA). In addition, myoepithelial cells were positive for alpha-SMA and CEA, which were scatterly positive for cytokeratin AE1/AE3, and negative for EMA. In examinations of non-palpable lesions found on mammography and ultrasound, a Mammotome biopsy is useful for making diagnosis, however, and adenomyoepithelioma is rarely found. In diagnosing such a rare disease from the limited information obtained from a needle biopsy, an immunohistochemical study was thus found to be useful for making a differential diagnosis.