Synthesis, Structure, and Biological Activity of [2.2]Paracyclophane Derivatives. 8. α-Pyridyl([2.2]paracyclophan-4-yl)-phenylmethanol: Structure of the Complex with Cu(II) Chloride and Intram
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- 作者：L. I. Kryvenko ; O. V. Zvolinskii ; A. T. Soldatenkov ; A. I. Kurbatova ; G. I. Dorofeeva ; L. N. Kuleshova and V. N. Khrustalev
- 关键词：α ; pyridyl([2.2]paracyclophan ; 4 ; yl)phenylmethanol ; [2.2]paracyclophano[4 ; 5 ; b]indolizine ; 1 ; phenyl ; 1 ; 1a ; dehydro ; 6 ; aza[3.2.2](1 ; 2 ; 5) ; 6H ; cyclophano[1 ; 2 ; a]pyridine ; complex with Cu(II) chloride ; heterocyclization ; luminescent properties
- 刊名：Chemistry of Heterocyclic Compounds
- 出版时间：June 2005
- 出版年：2005
- 期刊代码：19_00093122
- 类别：mat
- 卷：41
- 期：6
- 页码：745-753
- 数据来源：sp
摘要
The reaction of 2-benzoylpyridine with 4-([2.2]paracyclophanyl)lithium or of 4-benzoyl[2.2]paracyclophane with 2-pyridyllithium gave α-pyridyl([2.2]paracyclophan-4- yl)phenylmethanol. X-ray analysis has been used to study the molecular and crystalline structure of its complex with Cu(II) chloride. It was found that this triaryl-substituted methanol undergoes an intramolecular cyclocondensation in refluxing formic acid and involves the pyridine ring and the cyclophane substituent. Heterocyclization at the ortho-position of the latter gives 10-phenyl[2.2]paracyclophano[4,5-b]indolizine and cyclization at the pseudo-gem-position the 1-phenyl-1,1a-dehydro-6-aza[3.2.2](1,2,5)-6H-cyclophano[1,2-a]pyridine. The compounds prepared have luminescent properties.