Effect of exercise training and detraining on bone mineral density in postmenopausal women with osteoporosis
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- 作者：Jun Iwamoto ; Tsuyoshi Takeda and Shoichi Ichimura
- 关键词：Key words Osteoporosis ; Postmenopausal women ; Exercise training ; Detraining ; Bone mineral density (BMD)
- 刊名：Journal of Orthopaedic Science
- 出版时间：April 2001
- 出版年：2001
- 期刊代码：136_0949-2658
- 类别：med
- 卷：6
- 期：2
- 页码：128-132
- 数据来源：sp
摘要
We examined the effect of exercise training and detraining on bone mineral density (BMD) in postmenopausal women with osteoporosis. Thirty-five postmenopausal women with osteoporosis, aged 53–77 years, were randomly assigned to three groups: a control group (n = 20), a 2-year exercise training group (n = 8), and an 1-year exercise training plus 1-year detraining group (n = 7). Exercise training consisted of daily brisk walking and gymnastic training. Calcium lactate, 2.0 g, and 1α-hydroxyvitamin D3, 1 μg were supplied daily to all subjects. No significant differences in initial lumbar BMD, measured by dual-energy X-ray absorptiometry (DXA) were found among the three groups. The mean percent change in BMD compared with the baseline was significantly higher at 1 and 2 years in the exercise training group and at 1 year in the detraining group than in the control group, and did not differ significantly at 2 years between the detraining and control groups. These findings indicate that our exercise training program led to a significant increase in lumbar BMD in postmenopausal women with osteoporosis compared with the control, but that the BMD reverted toward a level that was not significantly different from the control with detraining. Continued exercise training is needed to maintain the bone mass gained through exercise training.