The pharmacological sensitivity of a touchscreen-based visual discrimination task in the rat using simple and perceptually challenging stimuli
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- 作者：J. C. Talpos (2) jtalpos@its.jnj.com
A. C. Fletcher (1)
C. Circelli (1)
M. D. Tricklebank (1)
S. L. Dix (1) - 关键词：MK ; 801 – ; PCP – ; d ; Amphetamine – ; Scopolamine – ; Memantine – ; Rat – ; Touchscreen – ; Visual discrimination – ; Schizophrenia – ; Perception
- 刊名：Psychopharmacology
- 出版时间：June 2012
- 出版年：2012
- 期刊代码：189_0033-3158
- 类别：med
- 卷：221
- 期：3
- 页码：437-449
- 数据来源：sp
摘要
Rationale Cognitive testing with touchscreen-equipped operant boxes (‘touchscreens’) is becoming increasingly popular. Tasks, such as paired associate learning or reversal learning of visual stimuli, have the discrimination of visual stimuli as a fundamental component. However, the effect of drugs commonly used in the study of cognitive mechanisms has yet to be described in a visual discrimination.