液相色谱-串联质谱在农药残留测定中的应用
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摘要
农药残留检测已经成为全球食品安全的重要组成部分。许多国家和国际组织都制定了严格的限量标准,规定了农产品中农药最大残留限量(MRLs),保证食品安全及进出口贸易。随着农药残留被广泛重视,分析方法不断发展,液相色谱-串联质谱因其高选择性、高灵敏度成为农药残留分析中最常用的检测技术之一。本文简述了最近两年液相色谱-串联质谱在农药残留分析中的应用,介绍了固相萃取及Qu ECh ERS净化方法、液相色谱分离以及串联质谱检测技术,包括低分辨串联质谱和高分辨串联质谱。
Pesticides residue analysis has become an important component of global food safety. Many countries and international organizations have established strict standards and set the maximum residue limits( MRLs) for pesticides in agricultural products,guaranteeing food safety and ensuring import and export trade. Liquid chromatography-tandem mass spectrometry( LC-MS/MS) has become a powerful technique for pesticide residue analysis due to its high specificity and sensitivity. This paper is to review the sample preparation and detection technologies of pesticide residues. The solid phase extraction( SPE) and Qu ECh ERS are introduced as well as liquid chromatography-tandem mass spectrometry( LC-MS/MS),including the liquid chromatography separation and the application of low resolution tandem mass spectrometry and the high resolution tandem mass spectrometry.
Pesticides residue analysis has become an important component of global food safety. Many countries and international organizations have established strict standards and set the maximum residue limits( MRLs) for pesticides in agricultural products,guaranteeing food safety and ensuring import and export trade. Liquid chromatography-tandem mass spectrometry( LC-MS/MS) has become a powerful technique for pesticide residue analysis due to its high specificity and sensitivity. This paper is to review the sample preparation and detection technologies of pesticide residues. The solid phase extraction( SPE) and Qu ECh ERS are introduced as well as liquid chromatography-tandem mass spectrometry( LC-MS/MS),including the liquid chromatography separation and the application of low resolution tandem mass spectrometry and the high resolution tandem mass spectrometry.
引文
[1]A.Valverde,A.Aguilera,A.Valverde-Monterreal.Food Control,2017,71:1
[2]P.Zhang,J.Ding,J.Hou,et al.Microchem J,2017,133:404
[3]Gong L P,Shi F,Jiang S Y,et al.Chinese J Chromatugr,2015,33:408巩丽萍,石峰,姜树银,等.色谱,2015,33:408
[4]Li M,Zhang J N,Meng X J.Biotech World,2016,13:62李曼,张嘉楠,孟宪杰.生物技术世界,2016,13:62
[5]S.Li,C.Lu,F.Zhu,et al.Anal Chim Acta,2015,873:57
[6]A.Andrade-Eiroa,M.Canle,V.Leroy-Cancellieri,et al.Tr AC-Trends Anal Chem,2016,80:655
[7]J.Liu,L.Tong,D.Li,et al.J Chromatogr B,2016,1017-1018:233
[8]A.Andrade-Eiroa,M.Canle,V.Leroy-Cancellieri,et al.Tr AC-Trends Anal Chem,2016,80:641
[9]J.Gan,L.Lv,J.Peng,et al.Food Chem,2016,207:195
[10]M.Zhang,K.Bian,T.Zhou,et al.J Chromatogr B,2016,1014:31
[11]A.M.Ares,S.Valverde,J.L.Bernal,et al.Food Chem,2017 232:169
[12]H.S.Lee,S.-W.Kim,A.M.Abd El-Aty,et al.J Chromatogr B,2017,1055-1056:172
[13]J.Potka-Wasylka,N.Szczepańska,M.de la Guardia,et al.Tr AC-Trends Anal Chem,2016,77:23
[14]Z.Shi,S.Zhang,Q.Huai,et al.Talanta,2017,162:300
[15]Q.Miao,J.Wang,J.Nie,et al.Anal.Methods,2016,8:5296
[16]W.A.Wan Ibrahim,H.R.Nodeh,H.Y.Aboul-Enein,et al.Crit Rev Anal Chem,2015,45:270
[17]I.Vasconcelos,C.Fernandes,Tr AC-Trends Anal Chem,2017,89:41
[18]H.Su,Y.Lin,Z.Wang,et al.J Chromatogr A,2016,1466:21
[19]P.Du,X.Wu,J.Xu,et al.Food Chem,2017,229:260
[20]Y.Xu,N.Song,Q.Zhang,et al.Food Chem,2017,221:205
[21]I.Machado,N.Gerez,M.Piston,et al.Food Chem,2017,227:227
[22]Y.Li,Z.Chen,R.Zhang,et al.Chromatog,2016,79:1165
[23]E.A.Nantia,D.Moreno-Gonzalez,F.P.Manfo,et al.Food Chem,2017,216:334
[24]J.A.Ferreira,J.M.Ferreira,V.Talamini,et al.Food Chem,2016,213:616
[25]F.Ribeiro Begnini Konatu,M.C.Breitkreitz,I.C.Sales Fontes Jardim,J Chromatogr A,2017,1482:11
[26]X.Dong,S.Liang,Z.Shi,et al.Food Chem,2017,192:432
[27]M.Hu,X.Liu,F.Dong,et al.Food Chem,2015,175:395
[28]P.A.S.Tette,F.A.da Silva Oliveira,E.N.C.Pereira,et al.Food Chem,2016,211:130
[29]A.Masia,M.M.Suarez-Varela,A.Llopis-Gonzalez,et al.Anal Chim Acta,2016,936:40
[30]T.M.Rizzetti,M.Kemmerich,M.L.Martins,et al.Food Chem,2017,196:25
[31]E.Dankyi,D.Carboo,C.Gordon,et al.J Food Compos Anal,2015,44:149
[32]A.Ucles,S.Herrera Lopez,M.Dolores Hernando,et al.Talanta,2015,144:51
[33]M..González-Curbelo,B.Socas-Rodríguez,A.V.Herrera-Herrera,et al.Tr AC-Trends Anal Chem,2015,71:169
[34]C.Cabrera Lda,S.S.Caldas,O.D.Prestes,et al.J Sep Sci,2016,39:1945
[35]Y.Han,N.Zou,L.Song,et al.J Chromatogr B,2015,1005:56
[36]Y.Han,L.Song,N.Zou,et al.J Chromatogr B,2016,1031:99
[37]P.Deme,V.V.R.Upadhyayula,Food Chem,2015,173:1142
[38]Y.L.Wu,R.X.Chen,Y.Zhu,et al.J Chromatogr B,2015,989:11
[39]Y.Qin,P.Zhao,S.Fan,et al.J Chromatogr A,2015,1385:1
[40]R.Lopez-Blanco,R.Nortes-Mendez,J.Robles-Molina,et al.J Chromatogr A,2016,1456:89
[41]P.Kaczynski,B.Lozowicka,M.Jankowska,et al.Talanta,2016,152:127
[42]O.Golge,B.Kabak,Food Chem,2015,176:319
[43]A.Masiá,M.M.Suarez-Varela,A.Llopis-Gonzalez,et al.Anal Chim Acta,2016,936:40
[44]S.Grimalt,P.Dehouck,J Chromatogr A,2016,1433:1
[45]X.P.Zhan,L.Ma,L.Q.Huang,et al.J Chromatogr B,2017,1060:281
[46]G.Bernardi,M.Kemmerich,L.C.Ribeiro,et al.Talanta,2016,161:40
[47]P.Sivaperumal,P.Anand,L.Riddhi,Food Chem,2015,168:356
[48]Y.Fu,T.Yang,J.Zhao,et al.Food chem,2017,218:192
[49]B.Reichert,I.R.Pizzutti,I.H.Costabeber,et al.Talanta,2015,134:415
[50]A.Ucles Moreno,S.Herrera Lopez,B.Reichert,et al.Anal Chem,2015,87:1018
[51]T.Poiger,I.J.Buerge,A.Bachli,et al.Environ Sci Pollut Res,2017,24:1588
[52]J.Wang,Z.Guo,A.Shen,et al.J Chromatogr A,2015 1398:29
[53]G.P.Danezis,C.J.Anagnostopoulos,K.Liapis,et al.Anal Chim Acta,2016,942:121
[54]P.Jandera,P.Janas,Anal Chim Acta,2017,967:12
[55]U.Bussy,K.Li,W.Li,Environ Sci Pollut Res,2016,23:9459
[56]F.Tang,Q.-W.Yu,B.-F.Yuan,et al.Tr AC-Trends Anal Chem,2017,86:172
[57]H.Guo,L.S.Riter,C.E.Wujcik,et al.J Chromatogr A,2016,1443:93
[58]I.R.Pizzutti,G.M.Vela,A.de Kok,et al.Food Chem,2016,209:248
[59]P.Kaczyński,Food Chem,2017,230:524
[60]R.Nortes-Mendez,J.Robles-Molina,R.Lopez-Blanco,et al.Talanta,2016,158:222
[61]C.Hao,M.R.Noestheden,X.Zhao,et al.Anal Chim Acta,2016,925:43
[62]W.Jiao,Y.Xiao,X.Qian,et al.Food Chem,2016,210:26
[63]M.E.Dasenaki,A.A.Bletsou,A.H.Hanafi,et al.Food Chem,2016,213:395
[64]I.Timofeeva,A.Shishov,D.Kanashina,et al.Talanta,2017,167:761
[65]P.A.Tette,L.Rocha Guidi,M.B.Gloria,et al.Talanta,2016,149:124
[66]C.Sack,J.Vonderbrink,M.Smoker,et al.J Agric Food Chem,2015,63:9657
[67]W.Yong,T.Guo,P.Fang,et al.Int J Mass Spectrom,2017,417:53
[68]Z.Jiang,H.Li,X.Cao,et al.Food Chem,2017,228:411
[69]Z.Zhang,M.Feng,K.Zhu,et al.J Agric Food Chem,2016,64:6091
[70]M.M.Rahman,A.M.Abd El-Aty,S.W.Kim,et al.Food Chem,2017,221:683
[71]Y.-J.Lee,M.M.Rahman,A.M.Abd El-Aty,et al.Food Chem,2016,210:442
[72]P.Kaczynski,Food Chem,2017,230:411
[73]O.Golge,B.Kabak,J Food Compos Anal,2015,41:86
[74]J.V.Dias,V.Cutillas,A.Lozano,et al.J Chromatogr A,2016,1462:8
[75]S.Dahane,M.D.G.García,A.U.Moreno,et al.Microchim Acta,2015,182:95
[76]Z.He,Y.Peng,L.Wang,et al.Chirality,2015,27:958
[77]Z.He,Y.Xu,L.Wang,et al.Food Chem,2016,196:1248
[78]N.I.Rousis,R.Bade,L.Bijlsma,et al.Environ Res,2017,156:31
[79]R.Guibal,S.Lissalde,A.Charriau,et al.J Chromatogr A,2015,1387:75
[80]A.Lopez,P.Dualde,V.Yusa,et al.Talanta,2016,160:547
[81]S.J.Lehotay,Y.Sapozhnikova,H.G.J.Mol,Tr AC-Trends Anal Chem,2015,69:62
[82]J.J.Villaverde,B.Sevilla-Morán,C.López-Goti,et al.Tr AC-Trends Anal Chem,2016,80:568
[83]A.Cortejade,A.Kiss,C.Cren,et al.Talanta,2016,146:694
[84]J.Cotton,F.Leroux,S.Broudin,et al.Water Res,2016,104:2
[85]S.Saito-Shida,S.Nemoto,R.Teshima,et al.Food Addit Contam,2016,33:119
[86]R.Su,D.Li,X.Wang,et al.J Chromatogr B,2016,1022:141
[2]P.Zhang,J.Ding,J.Hou,et al.Microchem J,2017,133:404
[3]Gong L P,Shi F,Jiang S Y,et al.Chinese J Chromatugr,2015,33:408巩丽萍,石峰,姜树银,等.色谱,2015,33:408
[4]Li M,Zhang J N,Meng X J.Biotech World,2016,13:62李曼,张嘉楠,孟宪杰.生物技术世界,2016,13:62
[5]S.Li,C.Lu,F.Zhu,et al.Anal Chim Acta,2015,873:57
[6]A.Andrade-Eiroa,M.Canle,V.Leroy-Cancellieri,et al.Tr AC-Trends Anal Chem,2016,80:655
[7]J.Liu,L.Tong,D.Li,et al.J Chromatogr B,2016,1017-1018:233
[8]A.Andrade-Eiroa,M.Canle,V.Leroy-Cancellieri,et al.Tr AC-Trends Anal Chem,2016,80:641
[9]J.Gan,L.Lv,J.Peng,et al.Food Chem,2016,207:195
[10]M.Zhang,K.Bian,T.Zhou,et al.J Chromatogr B,2016,1014:31
[11]A.M.Ares,S.Valverde,J.L.Bernal,et al.Food Chem,2017 232:169
[12]H.S.Lee,S.-W.Kim,A.M.Abd El-Aty,et al.J Chromatogr B,2017,1055-1056:172
[13]J.Potka-Wasylka,N.Szczepańska,M.de la Guardia,et al.Tr AC-Trends Anal Chem,2016,77:23
[14]Z.Shi,S.Zhang,Q.Huai,et al.Talanta,2017,162:300
[15]Q.Miao,J.Wang,J.Nie,et al.Anal.Methods,2016,8:5296
[16]W.A.Wan Ibrahim,H.R.Nodeh,H.Y.Aboul-Enein,et al.Crit Rev Anal Chem,2015,45:270
[17]I.Vasconcelos,C.Fernandes,Tr AC-Trends Anal Chem,2017,89:41
[18]H.Su,Y.Lin,Z.Wang,et al.J Chromatogr A,2016,1466:21
[19]P.Du,X.Wu,J.Xu,et al.Food Chem,2017,229:260
[20]Y.Xu,N.Song,Q.Zhang,et al.Food Chem,2017,221:205
[21]I.Machado,N.Gerez,M.Piston,et al.Food Chem,2017,227:227
[22]Y.Li,Z.Chen,R.Zhang,et al.Chromatog,2016,79:1165
[23]E.A.Nantia,D.Moreno-Gonzalez,F.P.Manfo,et al.Food Chem,2017,216:334
[24]J.A.Ferreira,J.M.Ferreira,V.Talamini,et al.Food Chem,2016,213:616
[25]F.Ribeiro Begnini Konatu,M.C.Breitkreitz,I.C.Sales Fontes Jardim,J Chromatogr A,2017,1482:11
[26]X.Dong,S.Liang,Z.Shi,et al.Food Chem,2017,192:432
[27]M.Hu,X.Liu,F.Dong,et al.Food Chem,2015,175:395
[28]P.A.S.Tette,F.A.da Silva Oliveira,E.N.C.Pereira,et al.Food Chem,2016,211:130
[29]A.Masia,M.M.Suarez-Varela,A.Llopis-Gonzalez,et al.Anal Chim Acta,2016,936:40
[30]T.M.Rizzetti,M.Kemmerich,M.L.Martins,et al.Food Chem,2017,196:25
[31]E.Dankyi,D.Carboo,C.Gordon,et al.J Food Compos Anal,2015,44:149
[32]A.Ucles,S.Herrera Lopez,M.Dolores Hernando,et al.Talanta,2015,144:51
[33]M..González-Curbelo,B.Socas-Rodríguez,A.V.Herrera-Herrera,et al.Tr AC-Trends Anal Chem,2015,71:169
[34]C.Cabrera Lda,S.S.Caldas,O.D.Prestes,et al.J Sep Sci,2016,39:1945
[35]Y.Han,N.Zou,L.Song,et al.J Chromatogr B,2015,1005:56
[36]Y.Han,L.Song,N.Zou,et al.J Chromatogr B,2016,1031:99
[37]P.Deme,V.V.R.Upadhyayula,Food Chem,2015,173:1142
[38]Y.L.Wu,R.X.Chen,Y.Zhu,et al.J Chromatogr B,2015,989:11
[39]Y.Qin,P.Zhao,S.Fan,et al.J Chromatogr A,2015,1385:1
[40]R.Lopez-Blanco,R.Nortes-Mendez,J.Robles-Molina,et al.J Chromatogr A,2016,1456:89
[41]P.Kaczynski,B.Lozowicka,M.Jankowska,et al.Talanta,2016,152:127
[42]O.Golge,B.Kabak,Food Chem,2015,176:319
[43]A.Masiá,M.M.Suarez-Varela,A.Llopis-Gonzalez,et al.Anal Chim Acta,2016,936:40
[44]S.Grimalt,P.Dehouck,J Chromatogr A,2016,1433:1
[45]X.P.Zhan,L.Ma,L.Q.Huang,et al.J Chromatogr B,2017,1060:281
[46]G.Bernardi,M.Kemmerich,L.C.Ribeiro,et al.Talanta,2016,161:40
[47]P.Sivaperumal,P.Anand,L.Riddhi,Food Chem,2015,168:356
[48]Y.Fu,T.Yang,J.Zhao,et al.Food chem,2017,218:192
[49]B.Reichert,I.R.Pizzutti,I.H.Costabeber,et al.Talanta,2015,134:415
[50]A.Ucles Moreno,S.Herrera Lopez,B.Reichert,et al.Anal Chem,2015,87:1018
[51]T.Poiger,I.J.Buerge,A.Bachli,et al.Environ Sci Pollut Res,2017,24:1588
[52]J.Wang,Z.Guo,A.Shen,et al.J Chromatogr A,2015 1398:29
[53]G.P.Danezis,C.J.Anagnostopoulos,K.Liapis,et al.Anal Chim Acta,2016,942:121
[54]P.Jandera,P.Janas,Anal Chim Acta,2017,967:12
[55]U.Bussy,K.Li,W.Li,Environ Sci Pollut Res,2016,23:9459
[56]F.Tang,Q.-W.Yu,B.-F.Yuan,et al.Tr AC-Trends Anal Chem,2017,86:172
[57]H.Guo,L.S.Riter,C.E.Wujcik,et al.J Chromatogr A,2016,1443:93
[58]I.R.Pizzutti,G.M.Vela,A.de Kok,et al.Food Chem,2016,209:248
[59]P.Kaczyński,Food Chem,2017,230:524
[60]R.Nortes-Mendez,J.Robles-Molina,R.Lopez-Blanco,et al.Talanta,2016,158:222
[61]C.Hao,M.R.Noestheden,X.Zhao,et al.Anal Chim Acta,2016,925:43
[62]W.Jiao,Y.Xiao,X.Qian,et al.Food Chem,2016,210:26
[63]M.E.Dasenaki,A.A.Bletsou,A.H.Hanafi,et al.Food Chem,2016,213:395
[64]I.Timofeeva,A.Shishov,D.Kanashina,et al.Talanta,2017,167:761
[65]P.A.Tette,L.Rocha Guidi,M.B.Gloria,et al.Talanta,2016,149:124
[66]C.Sack,J.Vonderbrink,M.Smoker,et al.J Agric Food Chem,2015,63:9657
[67]W.Yong,T.Guo,P.Fang,et al.Int J Mass Spectrom,2017,417:53
[68]Z.Jiang,H.Li,X.Cao,et al.Food Chem,2017,228:411
[69]Z.Zhang,M.Feng,K.Zhu,et al.J Agric Food Chem,2016,64:6091
[70]M.M.Rahman,A.M.Abd El-Aty,S.W.Kim,et al.Food Chem,2017,221:683
[71]Y.-J.Lee,M.M.Rahman,A.M.Abd El-Aty,et al.Food Chem,2016,210:442
[72]P.Kaczynski,Food Chem,2017,230:411
[73]O.Golge,B.Kabak,J Food Compos Anal,2015,41:86
[74]J.V.Dias,V.Cutillas,A.Lozano,et al.J Chromatogr A,2016,1462:8
[75]S.Dahane,M.D.G.García,A.U.Moreno,et al.Microchim Acta,2015,182:95
[76]Z.He,Y.Peng,L.Wang,et al.Chirality,2015,27:958
[77]Z.He,Y.Xu,L.Wang,et al.Food Chem,2016,196:1248
[78]N.I.Rousis,R.Bade,L.Bijlsma,et al.Environ Res,2017,156:31
[79]R.Guibal,S.Lissalde,A.Charriau,et al.J Chromatogr A,2015,1387:75
[80]A.Lopez,P.Dualde,V.Yusa,et al.Talanta,2016,160:547
[81]S.J.Lehotay,Y.Sapozhnikova,H.G.J.Mol,Tr AC-Trends Anal Chem,2015,69:62
[82]J.J.Villaverde,B.Sevilla-Morán,C.López-Goti,et al.Tr AC-Trends Anal Chem,2016,80:568
[83]A.Cortejade,A.Kiss,C.Cren,et al.Talanta,2016,146:694
[84]J.Cotton,F.Leroux,S.Broudin,et al.Water Res,2016,104:2
[85]S.Saito-Shida,S.Nemoto,R.Teshima,et al.Food Addit Contam,2016,33:119
[86]R.Su,D.Li,X.Wang,et al.J Chromatogr B,2016,1022:141