芪苈强心胶囊联合心脉隆注射液治疗难治性心力衰竭疗效观察
摘要
目的探讨芪苈强心胶囊联合心脉隆注射液治疗难治性心力衰竭的临床疗效。方法 106例难治性心力衰竭患者分为两组,观察组53例,西医常规治疗+芪苈强心胶囊+心脉隆注射液,对照组53例,西医常规治疗,治疗2周后比较两组患者心功能、血浆NT-proBNP水平。结果治疗后两组左室舒张末内径、心排出量、左室射血分数均较治疗前有改善,观察组改善的程度优于对照组(P<0.05),治疗后观察组血浆NT-proBNP水平低于对照组(P<0.05),临床疗效优于对照组(P<0.05)。结论在常规治疗的基础上加用芪苈强心胶囊和心脉隆能显著改善难治性心力衰竭心脏舒缩功能,降低其血浆NT-proBNP,提高生活质量和降低住院率,显著提高临床疗效。
引文
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[2]Roger VL,Go AS,Lloyd-Jones DM,et al.American Heart Association Statistics Committee and Stroke Statistics Subcommittee:Heart disease stroke statistics-2011 update A report from the American Heart Association[J].Circulation,2011,123(4):e1809.
[3]Juenger J,Schellberg D,Kraemer S,et al.Health related quality of life in patients with congestive heart failure Comparison with other chronic diseases and relation to functional variables[J].Heart,2002,87(3):235-241.
[4]全振华,艾民,金娟,等.芪苈强心胶囊对慢性心衰的治疗作用及机制的研究进展[J].中医药学报,2016,44(2):108-110.
[5]吴以岭.络病学基础与临床研究[M].北京:军事医学科学出版社,2010:353-367.
[6]张大程,张春雨,鹿梦溪.芪苈强心胶囊联合西药常规对慢性心力衰竭患者心室重构及相关免疫指标的影响[J].河北医药,2017,39(21):3209-3212
[7]徐涛,李方江,陈立峰,等.芪苈强心胶囊对心力衰竭大鼠心室重构的作用及机制研究[J].山东医药,2012,52(32):38-40.
[8]苏丽军,王建中,房志华.心脉隆注射液治疗慢性心力衰竭疗效观察[J]中西医结合心脑血管病杂志,2014,12(7):884-885.