核桃分心木成分分析及其功能性研究进展
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摘要
核桃分心木又称核桃隔,是夹在核仁之间的木质隔膜。传统中医发现其具有健脾固肾,利尿清热,涩精等功效,有较高的药用价值,我国民间常用来饮用,其他功能性方面研究尚在起步阶段。探讨了核桃分心木的化学成分以及抗菌、抗氧化、降糖、抑制脑功能衰退、抗肿瘤等多种功能活性,旨在为核桃分心木的深入研究和高效开发利用提供参考。
Walnut distracting wood, also known as walnut septum, is a woody membrane sandwiched between nucleoli.Traditional Chinese medicine found it had the benefits of spleen and kidney-fixing, diuretic heat, and astringent essence,and had a high medicinal value. It is commonly used by folks in China, but other functional aspects are still at the initial stage. This article discussed the chemical composition of Walnut centipede wood and its various functional activities such as antibacterial, antioxidant, hypoglycemic, inhibition of brain function decline, anti-tumor, etc. It aimed to provide reference for the in-depth research and efficient development and utilization of walnut distracting wood.
Walnut distracting wood, also known as walnut septum, is a woody membrane sandwiched between nucleoli.Traditional Chinese medicine found it had the benefits of spleen and kidney-fixing, diuretic heat, and astringent essence,and had a high medicinal value. It is commonly used by folks in China, but other functional aspects are still at the initial stage. This article discussed the chemical composition of Walnut centipede wood and its various functional activities such as antibacterial, antioxidant, hypoglycemic, inhibition of brain function decline, anti-tumor, etc. It aimed to provide reference for the in-depth research and efficient development and utilization of walnut distracting wood.
引文
[1]南京中医药大学.中药大辞典:上册[M].上海:上海科技出版社,2006:638.
[2]国家中医药管理局《中华本草》编委会.中华本草:第五卷[M].上海:上海科学技术出版社,1999:381.
[3]YAN L,WU W,DAN C,et al.Optimization of simultaneous microwave/ultrasonic-assisted extraction of phenolic compounds from walnut flour using response surface methodology[J].Pharmaceutical Biology,2017,55(1):1999.
[4]王艳梅,高莉,刘梦,等.核桃隔膜化学成分定性研究[J].食品工业科技,2008(12):123-124.
[5]毕肯·阿不得克里木,韩艳春,阿依吐伦·斯马义.核桃核桃分心木化学成分的预试验研究[J].新疆医科大学学报,2010,33(9):1 044-1 046.
[6]韩艳春.维吾尔药新疆核桃核桃分心木有效化学成分及其药理作用的研究[D].新疆:新疆医科大学,2010.
[7]杨明珠,周星利,王玎玮,等.核桃分心木化学成分研究[J].大理学院学报,2011,10(2):7-9.
[8]杨明珠,田新雁,肖朝江,等.核桃分心木化学成分与生物活性研究[J].天然产物研究与开发,2012,24(12):1 707-1 711.
[9]景援朝,赵焕新,孙永丽,等.核桃分心木化学成分的研究[J].食品与药品,2015,17(2):87-90.
[10]赵焕新,景援朝,白虹,等.核桃分心木中的化学成分及抗氧化活性研究[J].中国实验方剂学杂志,2016(7):54-57.
[11]李平,贾红婕,靳毓,等.核桃分心木水提液易挥发性成分分析[J].食品科学,2016,37(16):142-148.
[12]王艳梅,白洁,马木提·库尔班,等.核桃隔膜总黄酮和微量元素的测定[J].食品科学,2007,28(10):477-479.
[13]王国军,关丽,王幻,等.核桃隔膜不同提取物中黄酮类物质的含量测定[J].食品科技,2013(11):289-293.
[14]高莉,王强,帕提古力·玛合木提.核桃隔膜多糖的分离纯化及单糖组成分析[J].食品科学,2010,31(21):182-185.
[15]白洁,王艳梅,艾合买提江,等.分光光度法测新疆核桃核桃分心木中总生物碱含量[C].药用植物学国际学术研讨会,2007.
[16]付文焕,徐璐扬,施孝金,等.RP-HPLC测定核桃分心木中鞣质的水解物没食子酸[J].中国中药杂志,2007,32(8):748-749.
[17]付文焕,孙黎敏,朱婷,等.分心木的质量标准研究[J].中草药,2006,37(3):385-387.
[18]韩艳春,阿布都热合曼·合力力,阿依吐伦·斯马义.分光光度法测定维吾尔药核桃核桃分心木中总皂苷的含量[J].新疆医科大学学报,2010,33(3):286-287.
[19]王艳,茹仙古丽·哈斯木,韩艳春,等.苯酚-硫酸法测定维吾尔药核桃核桃分心木多糖的含量[J].亚太传统医药,2012,8(2):35-37.
[20]买买提·吐尔逊,阿吉姑·阿布都热西提,热萨莱提·伊敏,等.HPLC-PAD法测定不同品种核桃分心木中没食子酸、柚皮素[J].食品工业科技,2016,37(4):77-79.
[21]佚名.核桃核桃分心木治失眠[J].祝你幸福(中旬刊),2014(5):61-61.
[22]金龙,巴元明,李鸣.核桃分心木及其配伍在肾病临床的应用[J].湖北中医杂志,2010,32(4):60-61.
[23]关丽,张淑兰,王国军,等.核桃隔膜不同极性部位对肾阳虚小鼠的影响[J].兵团医学,2013,38(4):41-44.
[24]张天睿,杨爱玲,张天艺,等.核桃分心木镇静催眠作用探究[J].中国药事,2017,31(8):960-964.
[25]CUSHNIE TP,LAMB AJ.Antimicrobial activity of flavonoids.[J].International journal of antimicrobial agents,2005,26(5):343-356.
[26]高莉,王艳梅,帕提古丽·马合木提.核桃核桃分心木粗提物抑菌活性的研究[J].食品科学,2008,29(11):69-71.
[27]闫艳华,王鹏,杨卫民.核桃核桃分心木提取液抑菌效果初探[J].山西果树,2016(3):1-4.
[28]李橙橙.核桃分心木的初步开发利用[D].兰州:兰州大学,2010.
[29]古力伯斯坦艾达尔,吐热普江.核桃内隔膜总生物碱的提取及抑菌活性研究[J].天然产物研究与开发,2013,25(11):1 591-1 595.
[30]OLIVEIRA I,SOUSA A,FERREIRA IC,et al.Total phenols,antioxidant potential and antimicrobial activity of walnut(Juglans regia L.)green husks.[J].Food and Chemical Toxicology,2008,46(7):2 326-2 331.
[31]LI C,LIU J X,ZHAO L,et al.Capillary zone electrophoresis for separation and analysis of four diarylheptanoids and an alpha-tetralone derivative in the green walnut husks(Juglans regia L.)[J].Journal of Pharmaceutical&Biomedical Analysis,2008,48(3):749.
[32]徐蓓蓓.核桃副产物多酚的提取及其对油脂氧化稳定性的影响[D].阿拉尔:塔里木大学,2017.
[33]JELODAR G,MOHSEN M,SHAHRAM S.Effect of Walnut Leaf,Coriander and Pomegranate on Blood Glucose and Histopathology of Pancreas of Alloxan Induced Diabetic Rats[J].African Journal of Traditional Complementary&Alternative Medicines,2006,4(3):299-305.
[34]SHIRDEL Z,MADANI H,MIRBADALZADEH R.Investigation into the hypoglycemic effect of hydroalcoholic extract of Ziziphus Jujuba Leaves on blood glucose and lipids in Alloxan-Induced diabetes in rats[J].Iranian Journal of Diabetes&Lipid Disorders,2009,8(1):13-19.
[35]HAUPT E,PANTEN U.Die Stellung der Biguanide in der Therapie des Diabetes mellitus[J].Medizinische Klinik,1997,92(8):472-479.
[36]TEIMORI M,KOUHSARI S M,GHAFARZADEGAN R,et al.Study of hypoglycemic effect of Juglans regia leaves and its mechanism.[J].Journal of Medicinal Plants,2010,9(6):57-65.
[37]DEHGHANI F,MASHHOODI T,PANJEHSHAHIN M.Effect of Aqueous Extract of Walnut Septum on Blood Glucose and Pancreatic Structure in Streptozotocin-Induced Diabetic Mouse[J].Iranian Journal of Pharmacology&Therapeutics,2012,11(1):10-14.
[38]RENDEIRO C,RHODES J S,SPENCER J P.The mechanisms of action of flavonoids in the brain:Direct versus indirect effects.[J].Neurochemistry International,2015,89:126-139.
[39]令狐晨.新疆分心木体外抗肿瘤作用及其化学成分的研究[D].乌鲁木齐:新疆医科大学,2016.
[40]朱青梅.维吾尔药材核桃核桃分心木化学成分、质量标准及其活性研究[D].乌鲁木齐:新疆医科大学,2015.
[41]刘姗姗.核桃分心木袋泡茶制备工艺研究[D].乌鲁木齐:新疆农业大学,2015.
[42]张妍,杨海燕,阿迪拉,等.核桃分心木速溶茶的研制[J].农产品加工(下),2016(6):1-4.
[2]国家中医药管理局《中华本草》编委会.中华本草:第五卷[M].上海:上海科学技术出版社,1999:381.
[3]YAN L,WU W,DAN C,et al.Optimization of simultaneous microwave/ultrasonic-assisted extraction of phenolic compounds from walnut flour using response surface methodology[J].Pharmaceutical Biology,2017,55(1):1999.
[4]王艳梅,高莉,刘梦,等.核桃隔膜化学成分定性研究[J].食品工业科技,2008(12):123-124.
[5]毕肯·阿不得克里木,韩艳春,阿依吐伦·斯马义.核桃核桃分心木化学成分的预试验研究[J].新疆医科大学学报,2010,33(9):1 044-1 046.
[6]韩艳春.维吾尔药新疆核桃核桃分心木有效化学成分及其药理作用的研究[D].新疆:新疆医科大学,2010.
[7]杨明珠,周星利,王玎玮,等.核桃分心木化学成分研究[J].大理学院学报,2011,10(2):7-9.
[8]杨明珠,田新雁,肖朝江,等.核桃分心木化学成分与生物活性研究[J].天然产物研究与开发,2012,24(12):1 707-1 711.
[9]景援朝,赵焕新,孙永丽,等.核桃分心木化学成分的研究[J].食品与药品,2015,17(2):87-90.
[10]赵焕新,景援朝,白虹,等.核桃分心木中的化学成分及抗氧化活性研究[J].中国实验方剂学杂志,2016(7):54-57.
[11]李平,贾红婕,靳毓,等.核桃分心木水提液易挥发性成分分析[J].食品科学,2016,37(16):142-148.
[12]王艳梅,白洁,马木提·库尔班,等.核桃隔膜总黄酮和微量元素的测定[J].食品科学,2007,28(10):477-479.
[13]王国军,关丽,王幻,等.核桃隔膜不同提取物中黄酮类物质的含量测定[J].食品科技,2013(11):289-293.
[14]高莉,王强,帕提古力·玛合木提.核桃隔膜多糖的分离纯化及单糖组成分析[J].食品科学,2010,31(21):182-185.
[15]白洁,王艳梅,艾合买提江,等.分光光度法测新疆核桃核桃分心木中总生物碱含量[C].药用植物学国际学术研讨会,2007.
[16]付文焕,徐璐扬,施孝金,等.RP-HPLC测定核桃分心木中鞣质的水解物没食子酸[J].中国中药杂志,2007,32(8):748-749.
[17]付文焕,孙黎敏,朱婷,等.分心木的质量标准研究[J].中草药,2006,37(3):385-387.
[18]韩艳春,阿布都热合曼·合力力,阿依吐伦·斯马义.分光光度法测定维吾尔药核桃核桃分心木中总皂苷的含量[J].新疆医科大学学报,2010,33(3):286-287.
[19]王艳,茹仙古丽·哈斯木,韩艳春,等.苯酚-硫酸法测定维吾尔药核桃核桃分心木多糖的含量[J].亚太传统医药,2012,8(2):35-37.
[20]买买提·吐尔逊,阿吉姑·阿布都热西提,热萨莱提·伊敏,等.HPLC-PAD法测定不同品种核桃分心木中没食子酸、柚皮素[J].食品工业科技,2016,37(4):77-79.
[21]佚名.核桃核桃分心木治失眠[J].祝你幸福(中旬刊),2014(5):61-61.
[22]金龙,巴元明,李鸣.核桃分心木及其配伍在肾病临床的应用[J].湖北中医杂志,2010,32(4):60-61.
[23]关丽,张淑兰,王国军,等.核桃隔膜不同极性部位对肾阳虚小鼠的影响[J].兵团医学,2013,38(4):41-44.
[24]张天睿,杨爱玲,张天艺,等.核桃分心木镇静催眠作用探究[J].中国药事,2017,31(8):960-964.
[25]CUSHNIE TP,LAMB AJ.Antimicrobial activity of flavonoids.[J].International journal of antimicrobial agents,2005,26(5):343-356.
[26]高莉,王艳梅,帕提古丽·马合木提.核桃核桃分心木粗提物抑菌活性的研究[J].食品科学,2008,29(11):69-71.
[27]闫艳华,王鹏,杨卫民.核桃核桃分心木提取液抑菌效果初探[J].山西果树,2016(3):1-4.
[28]李橙橙.核桃分心木的初步开发利用[D].兰州:兰州大学,2010.
[29]古力伯斯坦艾达尔,吐热普江.核桃内隔膜总生物碱的提取及抑菌活性研究[J].天然产物研究与开发,2013,25(11):1 591-1 595.
[30]OLIVEIRA I,SOUSA A,FERREIRA IC,et al.Total phenols,antioxidant potential and antimicrobial activity of walnut(Juglans regia L.)green husks.[J].Food and Chemical Toxicology,2008,46(7):2 326-2 331.
[31]LI C,LIU J X,ZHAO L,et al.Capillary zone electrophoresis for separation and analysis of four diarylheptanoids and an alpha-tetralone derivative in the green walnut husks(Juglans regia L.)[J].Journal of Pharmaceutical&Biomedical Analysis,2008,48(3):749.
[32]徐蓓蓓.核桃副产物多酚的提取及其对油脂氧化稳定性的影响[D].阿拉尔:塔里木大学,2017.
[33]JELODAR G,MOHSEN M,SHAHRAM S.Effect of Walnut Leaf,Coriander and Pomegranate on Blood Glucose and Histopathology of Pancreas of Alloxan Induced Diabetic Rats[J].African Journal of Traditional Complementary&Alternative Medicines,2006,4(3):299-305.
[34]SHIRDEL Z,MADANI H,MIRBADALZADEH R.Investigation into the hypoglycemic effect of hydroalcoholic extract of Ziziphus Jujuba Leaves on blood glucose and lipids in Alloxan-Induced diabetes in rats[J].Iranian Journal of Diabetes&Lipid Disorders,2009,8(1):13-19.
[35]HAUPT E,PANTEN U.Die Stellung der Biguanide in der Therapie des Diabetes mellitus[J].Medizinische Klinik,1997,92(8):472-479.
[36]TEIMORI M,KOUHSARI S M,GHAFARZADEGAN R,et al.Study of hypoglycemic effect of Juglans regia leaves and its mechanism.[J].Journal of Medicinal Plants,2010,9(6):57-65.
[37]DEHGHANI F,MASHHOODI T,PANJEHSHAHIN M.Effect of Aqueous Extract of Walnut Septum on Blood Glucose and Pancreatic Structure in Streptozotocin-Induced Diabetic Mouse[J].Iranian Journal of Pharmacology&Therapeutics,2012,11(1):10-14.
[38]RENDEIRO C,RHODES J S,SPENCER J P.The mechanisms of action of flavonoids in the brain:Direct versus indirect effects.[J].Neurochemistry International,2015,89:126-139.
[39]令狐晨.新疆分心木体外抗肿瘤作用及其化学成分的研究[D].乌鲁木齐:新疆医科大学,2016.
[40]朱青梅.维吾尔药材核桃核桃分心木化学成分、质量标准及其活性研究[D].乌鲁木齐:新疆医科大学,2015.
[41]刘姗姗.核桃分心木袋泡茶制备工艺研究[D].乌鲁木齐:新疆农业大学,2015.
[42]张妍,杨海燕,阿迪拉,等.核桃分心木速溶茶的研制[J].农产品加工(下),2016(6):1-4.