腹腔镜手术对结直肠癌的治疗效果
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摘要
目的探索开腹手术和腹腔镜手术对结直肠癌的治疗效果及对术后肠梗阻发生率的影响。方法选取2017年3月26日—2018年3月26日我院结直肠癌100例患者(实施奇偶数法分组模式),对照组的50例患者进行开腹手术治疗,观察组的50例患者进行腹腔镜手术治疗,随后对比两组患者的并发症发生率、手术时间、肛门排气时间、切口总长度、淋巴结清扫数量、IgG、IgM、IL-6、CD4~+。结果观察组并发症发生率(2.00%)、手术时间(114.28±9.87)min、肛门排气时间(2.54±1.36)d、切口总长度(5.36±1.66)cm、淋巴结清扫数量(12.32±2.65)枚、IgG(131.48±8.35)IU/mL、IgM(152.63±7.84)IU/mL、IL-6(8.51±0.62)ng/L、CD4~+(25.68±1.68)均优于对照组(P<0.05)。结论对结直肠癌患者实施腹腔镜手术治疗效果显著,可降低术后肠梗阻率。
Objective To explore the therapeutic effect of open surgery and laparoscopic surgery on colorectal cancer and its effect on the incidence of postoperative intestinal obstruction. Methods 100 patients with colorectal cancer in our hospital from March 26, 2017 to March 26, 2018 were enrolled in the study. The 50 patients in the control group underwent laparotomy. The patient underwent laparoscopic surgery. Subsequently,the complication rate, operation time, anal exhaust time, total length of incision, number of lymph node dissection, IgG, IgM, IL-6, CD4~+ were compared between the two groups. Results The incidence of complications in the operation time(114.28±9.87) min, anal exhaust time(2.54±1.36) d,total incision length(5.36±1.66) cm, and lymph node dissection(12.32±2.65)The total incidence of postoperative intestinal obstruction(2.00%), IgG(131.48±8.35) IU/mL, IgM(152.63±7.84) IU/mL, IL-6(8.51±0.62) ng/L, CD4~+(25.68) ±1.68) were superior to the control group(P < 0.05). Conclusion Laparoscopic surgery is effective in patients with colorectal cancer, which can reduce the rate of postoperative intestinal obstruction.
Objective To explore the therapeutic effect of open surgery and laparoscopic surgery on colorectal cancer and its effect on the incidence of postoperative intestinal obstruction. Methods 100 patients with colorectal cancer in our hospital from March 26, 2017 to March 26, 2018 were enrolled in the study. The 50 patients in the control group underwent laparotomy. The patient underwent laparoscopic surgery. Subsequently,the complication rate, operation time, anal exhaust time, total length of incision, number of lymph node dissection, IgG, IgM, IL-6, CD4~+ were compared between the two groups. Results The incidence of complications in the operation time(114.28±9.87) min, anal exhaust time(2.54±1.36) d,total incision length(5.36±1.66) cm, and lymph node dissection(12.32±2.65)The total incidence of postoperative intestinal obstruction(2.00%), IgG(131.48±8.35) IU/mL, IgM(152.63±7.84) IU/mL, IL-6(8.51±0.62) ng/L, CD4~+(25.68) ±1.68) were superior to the control group(P < 0.05). Conclusion Laparoscopic surgery is effective in patients with colorectal cancer, which can reduce the rate of postoperative intestinal obstruction.
引文
[1]杨小峰,苏文斌,邓子清,等.腹腔镜下腹部无切口结直肠癌切除对比传统腹腔镜下结直肠癌切除可行性和安全性的Meta分析[J].中南大学学报(医学版),2017,42(1):88-97.
[2]梁家强.腹腔镜结直肠癌根治术后患者血清炎症、凝血及疼痛因子水平变化[J].山东医药,2018,58(30):68-71.
[3]霍雄伟,王效龙,魏光兵,等.手辅助腹腔镜与腹腔镜辅助手术治疗结直肠癌的对比研究[J].西安交通大学学报(医学版),2017,38(1):92-95,126.
[4]蔡楚东,周俊怿,方喜.腹腔镜微创根治术对结直肠癌患者疼痛及免疫功能的影响[J].广东医学,2017,38(15):2350-2352.
[5]王国森,周建平,盛伟伟,等.手辅助腹腔镜、腹腔镜辅助和开腹结直肠癌手术近期疗效的比较[J].中国医科大学学报,2017,46(2):126-130,135.
[6]郭鹏,张治清,兰远志,等.腹腔镜结直肠癌根治术联合肝转移灶射频消融术与开腹结直肠癌肝转移根治术的疗效分析[J].中华消化外科杂志,2018,17(5):459-465.
[7]周德全,徐亮.腹腔镜与开腹结直肠癌切除术远期生存率和并发症的Meta分析[J].实用医学杂志,2016,32(2):291-294.
[8]徐飞鹏,许庆文,鲁珏,等.腹腔镜辅助与开腹结直肠癌根治术治疗Ⅱ、Ⅲ期结直肠癌机体免疫反应的影响[J].中华实验外科杂志,2015,32(12):3164-3166.
[9]魏微微,张雪梅,田浩,等.腹腔镜结直肠癌根治术对结直肠癌患者细胞免疫功能、胃肠激素及预后的影响[J].中国内镜杂志,2018,24(12):1-6.
[10]马克,王祥宇,陈进宏.同时性结直肠癌肝转移腹腔镜同期切除术与开腹手术的比较研究[J].中华外科杂志,2018,56(7):516-521.
[11]闫观升,王志广,刘龙.术前区域动脉灌注化疗联合腹腔镜手术治疗结直肠癌的短期疗效分析[J].结直肠肛门外科,2015,21(S1):61-62.
[12]陈文斌,周建树,周江川,等.腹腔镜手术与传统根治术治疗结直肠癌的效果对比[J].中国当代医药,2015,8(20):54-56.
[2]梁家强.腹腔镜结直肠癌根治术后患者血清炎症、凝血及疼痛因子水平变化[J].山东医药,2018,58(30):68-71.
[3]霍雄伟,王效龙,魏光兵,等.手辅助腹腔镜与腹腔镜辅助手术治疗结直肠癌的对比研究[J].西安交通大学学报(医学版),2017,38(1):92-95,126.
[4]蔡楚东,周俊怿,方喜.腹腔镜微创根治术对结直肠癌患者疼痛及免疫功能的影响[J].广东医学,2017,38(15):2350-2352.
[5]王国森,周建平,盛伟伟,等.手辅助腹腔镜、腹腔镜辅助和开腹结直肠癌手术近期疗效的比较[J].中国医科大学学报,2017,46(2):126-130,135.
[6]郭鹏,张治清,兰远志,等.腹腔镜结直肠癌根治术联合肝转移灶射频消融术与开腹结直肠癌肝转移根治术的疗效分析[J].中华消化外科杂志,2018,17(5):459-465.
[7]周德全,徐亮.腹腔镜与开腹结直肠癌切除术远期生存率和并发症的Meta分析[J].实用医学杂志,2016,32(2):291-294.
[8]徐飞鹏,许庆文,鲁珏,等.腹腔镜辅助与开腹结直肠癌根治术治疗Ⅱ、Ⅲ期结直肠癌机体免疫反应的影响[J].中华实验外科杂志,2015,32(12):3164-3166.
[9]魏微微,张雪梅,田浩,等.腹腔镜结直肠癌根治术对结直肠癌患者细胞免疫功能、胃肠激素及预后的影响[J].中国内镜杂志,2018,24(12):1-6.
[10]马克,王祥宇,陈进宏.同时性结直肠癌肝转移腹腔镜同期切除术与开腹手术的比较研究[J].中华外科杂志,2018,56(7):516-521.
[11]闫观升,王志广,刘龙.术前区域动脉灌注化疗联合腹腔镜手术治疗结直肠癌的短期疗效分析[J].结直肠肛门外科,2015,21(S1):61-62.
[12]陈文斌,周建树,周江川,等.腹腔镜手术与传统根治术治疗结直肠癌的效果对比[J].中国当代医药,2015,8(20):54-56.