摘要
目的:了解首都医科大学密云教学医院手术患者围术期预防性应用抗菌药物情况,促进临床合理使用抗菌药物。方法:对2017—2018年我院上报全国抗菌药物临床应用监测网的360例手术病例进行回顾性分析,依据国家卫生健康委员会的相关规定,对抗菌药物的品种选择、给药时间、用药疗程和联合用药等指标进行评价与分析。结果:360例手术患者中,212例预防性应用抗菌药物,抗菌药物预防性使用率为58.89%;29例治疗性使用抗菌药物;119例未使用抗菌药物。其中,Ⅰ类切口手术围术期抗菌药物预防性使用率为29.17%(35/120),符合相关规定(≤30%);Ⅱ类切口手术围术期抗菌药物预防性使用率为80.82%(177/219);Ⅲ类切口手术治疗性使用抗菌药物21例。头孢菌素类抗菌药物的预防性使用率最高,部分病例药品选择、用药疗程不符合相关规定。结论:我院手术患者围术期抗菌药物的使用仍存在一些问题,需进一步加强抗菌药物的应用管理和药学干预。
ABSTACT OBJECTIVE: To investigate the prophylactic application of antibiotics during perioperative period in Miyun Teaching Hospital Affiliated to Capital Medical University(hereinafter referred to as "our hospital"), so as to promote clinical rational application of antibiotics. METHODS: 360 surgical cases in our hospital during 2017-2018 reported to the Center for Antibacterial Surveillance were retrospectively analyzed, according to relevant regulations of National Health Commission, the cases were evaluated and analyzed in terms of drug selection, drug administration time, treatment course and drug combination, etc. RESULTS: Among the 360 patients, 212 cases were prophylactically applies with antibiotics, with the rate was 58.89%; 29 cases were therapeutically applied with antibiotics; 119 cases were not used antibiotics. Among them, the prophylactic application rate of antibiotics during perioperative period of type Ⅰ incision was 29.17%(35/120), which complied with relevant regulations(≤30%); the prophylactic application rate of antibiotics during perioperative period of type Ⅱ incision was 80.82%(177/219); the number of therapeutic application of antibiotics in type Ⅲ incision was 21 cases. The prophylactic application rate of cephalosporins antibiotics was the highest, the drug selection and treatment course in some cases do not meet the relevant regulations. CONCLUSIONS: There are still some problems in the application of antibiotics during perioperative period, which is necessary to further strengthen its application management and pharmaceutical intervention.
引文
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