杜仲不同“发汗”加工方法制品中总黄酮含量的比较
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摘要
目的比较不同"发汗"加工方法对杜仲总黄酮含量的影响,为杜仲加工增效提供理论依据。方法采用紫外分光光度法测定杜仲总黄酮含量。结果与生品比较,传统"发汗"加工方法对总黄酮含量的影响无显著性差异;其他"发汗"加工方法差异显著(P﹤0. 05或P﹤0. 01)。与传统"发汗"加工方法比较:阴至半干后"发汗"对总黄酮含量影响显著(P﹤0. 05);晒至半干后"发汗"、烘至半干后"发汗"、煮后"发汗"和蒸后"发汗"对总黄酮含量影响极显著(P﹤0. 01)。结论临床应用以杜仲总黄酮的药理作用为主时,建议采用蒸后"发汗"加工方法的制品。
Objective Study on the effect of different sweating processing methods on the contents of total flavone to provide scientific basis for further research on processing methods and enhancing efficacy. Methods The sample was determined by UV-Vis spectrophotometer.Results Compared with the raw products,the traditional sweating processing method has no significant difference on the contents of total flavone while the other sweating processing method has(P﹤0. 05 or P﹤0. 01).And compared with the products processed by traditional sweating methods sweating after semi-dry in the shade(P﹤0. 05),sweating after semi-dry in the sun,in the oven and sweating after boil and steam(P﹤0. 01)both has significant differences. Conclusion Considering the pharmacological action of total flavone in the clinic,suggest using the products processed by sweating after steam.
Objective Study on the effect of different sweating processing methods on the contents of total flavone to provide scientific basis for further research on processing methods and enhancing efficacy. Methods The sample was determined by UV-Vis spectrophotometer.Results Compared with the raw products,the traditional sweating processing method has no significant difference on the contents of total flavone while the other sweating processing method has(P﹤0. 05 or P﹤0. 01).And compared with the products processed by traditional sweating methods sweating after semi-dry in the shade(P﹤0. 05),sweating after semi-dry in the sun,in the oven and sweating after boil and steam(P﹤0. 01)both has significant differences. Conclusion Considering the pharmacological action of total flavone in the clinic,suggest using the products processed by sweating after steam.
引文
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[12] 胡慧玲,卫莹芳,马雪玮,等.不同加工方法对厚朴主要化学成分的影响研究[J].中成药,2011,33(5):834.
[2] 张才超,袁带秀,李玲,等.杜仲总黄酮对H2O2诱导的IEC-6细胞氧化损伤的保护作用[J].中国临床药理学与治疗学,2015,20(10):1106.
[3] 袁带秀,舒丽霞,黄荣.杜仲总黄酮对荷瘤小鼠的抗肿瘤作用[J].中国临床药理学与治疗学,2014,19(12):1332.
[4] 王志宏,雷明盛,彭胜,等.杜仲黄酮对小鼠淋巴细胞增殖及IL-2和IFN-γ诱生的影响[J].天然产物研究与开发,2016,28(4):514.
[5] 刘静,濮智颖,李爱玲,等.杜仲叶黄酮降血脂及抗氧化作用的研究[J].安徽农业科学,2010,38(11):5631.
[6] 袁真,闵珺,王恺,等.杜仲黄酮类3种药物成分治疗大鼠骨质疏松的比较研究[J].中国骨质疏松杂志,2018,24(2):244.
[7] 杨亚旭,孔桂美,朱琦,等.蜂毒素联合杜仲黄酮外用治疗类风湿关节炎的实验研究[J].时珍国医国药,2016,252(8):1833.
[8] 王丽娜,杨美华.传统发汗方法对杜仲降压作用的影响[C].中国药学会:2010年中国药学大会暨第十届中国药师周论文集,2010:5160.
[9] 徐丽萍,喻方圆,陈浩,等.超声波提取杜仲皮总黄酮工艺[J].林业科技开发,2010,24(4):82.
[10] 王娟娟,秦血梅,高晓霞,等.杜仲化学成分、药理活性和质量控制现状研究进展[J].中草药,2017,48(15):3228.
[11] 刘艳,李玮,王建科,等.综合评分法优选川续断产地加工方法[J].中药材,2012,35(12):1922.
[12] 胡慧玲,卫莹芳,马雪玮,等.不同加工方法对厚朴主要化学成分的影响研究[J].中成药,2011,33(5):834.