中医药治疗胆总管结石的研究进展
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摘要
胆总管结石作为临床多发病,逐渐得到人们的重视,如何更好地发挥中医药的治疗作用也不断为大家探讨。本文拟从胆总管结石的中医认识、中医药治疗本病的临床观察、动物实验、不同大小结石的中医药治疗方案选择等方面予以综述,并根据目前主要研究方向,提出未来可努力的治疗方向,并言明其可能性,以为临床服务。
Choledocholithiasis, as a frequently-occurring clinical disease, has been paid more and more attention. How to better play the role of traditional Chinese medicine treatment is also constantly discussed for us. This paper aims to summarize the traditional Chinese medicine understanding of choledocholithiasis, the clinical observation of traditional Chinese medicine treatment of this disease, animal experiments, and the selection of traditional Chinese medicine treatment plans for stones of different sizes. According to the current research direction, this paper puts forward the treatment direction that can be worked on in the future and states its possibility, so that it can serve the clinic.
Choledocholithiasis, as a frequently-occurring clinical disease, has been paid more and more attention. How to better play the role of traditional Chinese medicine treatment is also constantly discussed for us. This paper aims to summarize the traditional Chinese medicine understanding of choledocholithiasis, the clinical observation of traditional Chinese medicine treatment of this disease, animal experiments, and the selection of traditional Chinese medicine treatment plans for stones of different sizes. According to the current research direction, this paper puts forward the treatment direction that can be worked on in the future and states its possibility, so that it can serve the clinic.
引文
[1]国海超,党彤.胆总管结石成因的研究进展[J].中国继续医学教育,2016,8(24):81-82.
[2]张学文,杨永生,张丹.肝内胆管结石分型及治疗方法选择[J].中国实用外科杂志,2009,29(9):790-792,795.
[3]韩天权,蒋兆彦,张圣道.胆固醇结石形成机制的基因研究现状与展望[J].外科理论与实践,2009,14(2):125-127.
[4] Guo L,Mao J,Li Y,et al. Cholelithiasis,cholecystectomy and risk of hepatocellular carcinoma:a meta-analysis[J]. J Cancer Res Ther,2014,10(4):834-838.
[5] Uchiyama K,Onishi H,Tani M,et al. Long-term prognosis after treatment of patients with choledocholithiasis[J]. Ann Surg,2003,238(1):97-102.
[6]戴红卫.胆石症中医辨证分型与B超图像的相关性分析[J].中国中医药现代远程教育,2015,13(3):51-52.
[7]刘芳,陕大艳,陈启明,等.胆石症中医辨证分型与B超特征关系的探讨[J].中医学报,2014,29(7):1045-1046.
[8]韩丽霞,王晴,董秀敏.调中溶石汤治疗肝胆气郁型胆总管结石76例疗效观察[J].北京中医药,2012,31(1):60-61.
[9]于丽,高文艳,刘杨,等.林一帆“从肝论治”胆总管结石经验总结[J].辽宁中医杂志,2014,41(4):632-634.
[10]孙波.茵柴合剂治疗改善胆总管结石合并肝功能损害的临床研究[D].济南:山东中医药大学,2008.
[11]巩阳,林一帆,王长洪,等.化石利胆汤对ERCP术后胆总管结石患者CYP7A1和B-UGT影响研究[J].中国中医基础医学杂志,2011,17(6):655-657.
[12]高矩,朱培庭,张静喆,等.养肝柔肝法防治胆色素结石中干预胆道动力学异常的机理研究[J].中国中西医结合外科杂志,2002,8(6):15-18.
[13]张西波,崔乃强,李东华.清热利湿方防治兔胆色素结石形成的实验研究[J].中国中西医结合杂志,2007,27(3):241-243.
[14]张静喆,梁晓强,章学林,等.清胆胶囊与养肝利胆颗粒对豚鼠胆色素结炎症反应环节的影响[J].上海中医药大学学报,2009,23(5):51-54.
[15]孙立波,冯野,李国栋,等.胆总管残留、复发结石的中药排石治疗[J].现代中西医结合杂志,2004,13(1):52-53.
[16]刘君颖.中药治疗胆总管结石逆行胰胆管造影术术后并发症的研究现状[J].中医杂志,2013,54(23):2056-2059.
[17]王业忠,夏兴洲,杨恩茹,等.经十二指肠镜胆总管结石首次取石失败的原因分析[J].临床荟萃,2005,20(2):80-81.
[18]王长洪,杨卓,麻树人.鼻胆管注入溶石中药治疗胆总管较大结石疗效观察[J].中国中西医结合消化杂志,2007,15(4):234-236.
[19]贾琦.三联排石疗法治疗胆总管结石的临床研究[D].合肥:安徽中医药大学,2016.
[20]李志雄,黄玉萍,陈锦锋,等.胆总管结石行经十二指肠镜逆行胰胆管造影术加内镜下乳头括约肌切开术的中医证型变化研究[J].中国中医急症,2017,26(10):1744-1746.
[21]陈金保.四逆散方证研究及临床应用规律探讨[D].北京:中国中医科学院,2007.
[22]温静.四逆散抗肝损伤药效物质基础与配伍机理研究[D].沈阳:沈阳药科大学,2012.
[23]叶富强,陈蔚文.四君子汤对胃肠道作用的药理研究[J].时珍国医国药,2005,16(1):73-74.
[24]魏彦明,宗瑞谦,杨孝朴.实验性脾虚证大鼠血浆胃泌素和胃动素含量变化及四君子汤对其调整作用[J].中国兽医学报,2001,21(3):281-283.
[25]陈晓文,智发朝,曹东林.胃动素及生长抑素在胆总管结石形成中作用探讨[J].中国民康医学,2008,20(1):23,25.
[2]张学文,杨永生,张丹.肝内胆管结石分型及治疗方法选择[J].中国实用外科杂志,2009,29(9):790-792,795.
[3]韩天权,蒋兆彦,张圣道.胆固醇结石形成机制的基因研究现状与展望[J].外科理论与实践,2009,14(2):125-127.
[4] Guo L,Mao J,Li Y,et al. Cholelithiasis,cholecystectomy and risk of hepatocellular carcinoma:a meta-analysis[J]. J Cancer Res Ther,2014,10(4):834-838.
[5] Uchiyama K,Onishi H,Tani M,et al. Long-term prognosis after treatment of patients with choledocholithiasis[J]. Ann Surg,2003,238(1):97-102.
[6]戴红卫.胆石症中医辨证分型与B超图像的相关性分析[J].中国中医药现代远程教育,2015,13(3):51-52.
[7]刘芳,陕大艳,陈启明,等.胆石症中医辨证分型与B超特征关系的探讨[J].中医学报,2014,29(7):1045-1046.
[8]韩丽霞,王晴,董秀敏.调中溶石汤治疗肝胆气郁型胆总管结石76例疗效观察[J].北京中医药,2012,31(1):60-61.
[9]于丽,高文艳,刘杨,等.林一帆“从肝论治”胆总管结石经验总结[J].辽宁中医杂志,2014,41(4):632-634.
[10]孙波.茵柴合剂治疗改善胆总管结石合并肝功能损害的临床研究[D].济南:山东中医药大学,2008.
[11]巩阳,林一帆,王长洪,等.化石利胆汤对ERCP术后胆总管结石患者CYP7A1和B-UGT影响研究[J].中国中医基础医学杂志,2011,17(6):655-657.
[12]高矩,朱培庭,张静喆,等.养肝柔肝法防治胆色素结石中干预胆道动力学异常的机理研究[J].中国中西医结合外科杂志,2002,8(6):15-18.
[13]张西波,崔乃强,李东华.清热利湿方防治兔胆色素结石形成的实验研究[J].中国中西医结合杂志,2007,27(3):241-243.
[14]张静喆,梁晓强,章学林,等.清胆胶囊与养肝利胆颗粒对豚鼠胆色素结炎症反应环节的影响[J].上海中医药大学学报,2009,23(5):51-54.
[15]孙立波,冯野,李国栋,等.胆总管残留、复发结石的中药排石治疗[J].现代中西医结合杂志,2004,13(1):52-53.
[16]刘君颖.中药治疗胆总管结石逆行胰胆管造影术术后并发症的研究现状[J].中医杂志,2013,54(23):2056-2059.
[17]王业忠,夏兴洲,杨恩茹,等.经十二指肠镜胆总管结石首次取石失败的原因分析[J].临床荟萃,2005,20(2):80-81.
[18]王长洪,杨卓,麻树人.鼻胆管注入溶石中药治疗胆总管较大结石疗效观察[J].中国中西医结合消化杂志,2007,15(4):234-236.
[19]贾琦.三联排石疗法治疗胆总管结石的临床研究[D].合肥:安徽中医药大学,2016.
[20]李志雄,黄玉萍,陈锦锋,等.胆总管结石行经十二指肠镜逆行胰胆管造影术加内镜下乳头括约肌切开术的中医证型变化研究[J].中国中医急症,2017,26(10):1744-1746.
[21]陈金保.四逆散方证研究及临床应用规律探讨[D].北京:中国中医科学院,2007.
[22]温静.四逆散抗肝损伤药效物质基础与配伍机理研究[D].沈阳:沈阳药科大学,2012.
[23]叶富强,陈蔚文.四君子汤对胃肠道作用的药理研究[J].时珍国医国药,2005,16(1):73-74.
[24]魏彦明,宗瑞谦,杨孝朴.实验性脾虚证大鼠血浆胃泌素和胃动素含量变化及四君子汤对其调整作用[J].中国兽医学报,2001,21(3):281-283.
[25]陈晓文,智发朝,曹东林.胃动素及生长抑素在胆总管结石形成中作用探讨[J].中国民康医学,2008,20(1):23,25.