正常妊娠孕妇不同孕期血常规参数变化的分析
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摘要
目的分析正常妊娠孕妇不同孕期血常规参数的变化情况,为孕期保健和妊娠期相关疾病的诊治提供参考依据。方法产科门诊进行产前检查的233例正常妊娠孕妇,按照妊娠时期分为妊娠早期组73例、妊娠中期组79例、妊娠晚期组81例,另选在我院体检的72例健康女性作为正常对照组;采集4组人群晨起空腹静脉血3 mL,采用贝克曼库尔特全自动血液分析仪测定白细胞(WBC)、中性粒细胞百分比(NEUT%)、淋巴细胞百分比(LY%)、红细胞(RBC)、血红蛋白(HGB)、红细胞压积(HCT)、血小板(PLT),对检测结果进行统计学分析。结果与正常对照组相比,妊娠期3组孕妇的WBC和NEUT%水平均升高,LY%、RBC、HGB和HCT均明显降低,差异有统计学意义(P<0.05)。与妊娠早期组比较,妊娠中期组和妊娠晚期组的WBC、NEUT%水平升高,LY%、PLT水平降低,差异有统计学意义(P<0.05);妊娠中期组和妊娠晚期组的WBC、NEUT%、LY%差异无统计学意义(P>0.05)。妊娠早期组RBC、HGB、HCT水平显著高于妊娠晚期组和妊娠中期组(P<0.05),妊娠晚期组显著高于妊娠中期组(P<0.05)。结论不同孕期正常妊娠孕妇血常规相关参数均发生了不同程度的变化。
Objective To identity the pattern of changes of indicators in complete blood count(CBC) in pregnant women at different stages of normal pregnancy so as to obtain scientific knowledge to inform practitioners of nursing care and treatment of diseases during pregnancy. Methods Firstly, 233 women with normal pregnancy admitted to the obstetrics department for pre-delivery check-up were divided into three groups in accordance with the gestational period into which their length of pregnancy fell, namely, group 1(n=73, early stage), group 2(n=79, second trimester), and group 3(n=81, the third trimester). Another 72 healthy women admitted for physical examination were were chosen as the control group. 3 mL of morning fasting venous blood was collected from each member of the four groups and tested for white blood cells(WBC), neutrophil percentage(NEUT%), lymphocyte percentage(LY%), red blood cell(RBC), hemoglobin(HGB), hematocrit(HCT), and platelet(PLT). Next, the results were subjected to statistics analysis. Results Compared with those of the control group, the WBC and NEUT% levels of all pregnant women in the three groups became higher. The levels of LY%, RBC, HGB and HCT became lower. The differences were statistically significant(P<0.05). Compared with those of group 1, the WBC and NEUT% levels of group 2 and group 3 became higher. The LY% and PLT levels became lower. The differences were statistically significant(P<0.05). No significant differences were found between group 2 and group 3 in WBC, NEUT% and LY%(P>0.05). The levels of RBC, HGB and HCT of group 1 were significantly higher than those of group 2 and group 3(P<0.05), with those of group 3 being higher than those of group 2(P<0.05). Conclusions Changes of indicators of CBC occur in women at different trimesters of normal pregancy.
Objective To identity the pattern of changes of indicators in complete blood count(CBC) in pregnant women at different stages of normal pregnancy so as to obtain scientific knowledge to inform practitioners of nursing care and treatment of diseases during pregnancy. Methods Firstly, 233 women with normal pregnancy admitted to the obstetrics department for pre-delivery check-up were divided into three groups in accordance with the gestational period into which their length of pregnancy fell, namely, group 1(n=73, early stage), group 2(n=79, second trimester), and group 3(n=81, the third trimester). Another 72 healthy women admitted for physical examination were were chosen as the control group. 3 mL of morning fasting venous blood was collected from each member of the four groups and tested for white blood cells(WBC), neutrophil percentage(NEUT%), lymphocyte percentage(LY%), red blood cell(RBC), hemoglobin(HGB), hematocrit(HCT), and platelet(PLT). Next, the results were subjected to statistics analysis. Results Compared with those of the control group, the WBC and NEUT% levels of all pregnant women in the three groups became higher. The levels of LY%, RBC, HGB and HCT became lower. The differences were statistically significant(P<0.05). Compared with those of group 1, the WBC and NEUT% levels of group 2 and group 3 became higher. The LY% and PLT levels became lower. The differences were statistically significant(P<0.05). No significant differences were found between group 2 and group 3 in WBC, NEUT% and LY%(P>0.05). The levels of RBC, HGB and HCT of group 1 were significantly higher than those of group 2 and group 3(P<0.05), with those of group 3 being higher than those of group 2(P<0.05). Conclusions Changes of indicators of CBC occur in women at different trimesters of normal pregancy.
引文
[1] 李晓峰,常红叶,齐力,等.临床血常规检验中不同采血方式的结果分析[J].中国实验诊断学,2016,20(6):1021-1022.
[2] 陈婉珍,闫颖,吴林玲.妊娠期妇女阴道微生态研究进展[J].中国微生态学杂志,2016,28(4):489-492.
[3] 赵旭宏,徐怡嘉,侯军林.妊娠期妇女不同孕期白细胞及血小板生理变化分析[J].中国卫生检验杂志,2016,26(2):217-218.
[4] 奚伟红.不同孕期健康孕妇血脂检测的研究及临床意义[J].检验医学与临床,2017,14(A02):330-331.
[5] 仓沈元,翟光华,尹娟,等.血清铁蛋白、叶酸、维生素B-12检测对妊娠期妇女不同孕期的临床意义[J].检验医学与临床,2017,14(11):1635-1637.
[6] 周青雪,董世雷,施晓春,等.不同年龄段不同孕期孕妇体内微量元素含量的比较与分析[J].中国卫生检验杂志,2016(21):3155-3157.
[7] 石艳艳,罗红权,李宁,等.正常妊娠妇女不同孕期血常规参数变化的研究[J].检验医学与临床,2016,13(17):2442-2443.
[8] 崔贺然,全贞玉.白细胞计数及其分类与妊娠期高血压疾病的相关性研究[J].中国妇幼保健,2016,31(3):468-470.
[9] 李星,常颖,陈叙.正常孕产妇剖宫产分娩前后全血细胞参数的变化分析[J].国际妇产科学杂志,2016,43(1):32-35.
[10] 陈小燕,魏花.妊娠期贫血患者的血常规检验分析[J].中国医药导刊,2016,18(9):947-948.
[11] 邓青春,潘英连,常青,等.正常妊娠妇女临产及顺产后24h血常规检测参考区间相关研究[J].重庆医学,2016,45(5):617-618.
[12] 石中华,丁虹娟.妊娠合并血小板减少的病因及诊疗策略[J].实用妇产科杂志,2016,32(9):649-652.
[13] 杨敏,郭志伟,蒋婕.妊娠合并血小板减少症的病因分析及对母婴结局的影响[J].中国妇幼保健,2017,32(6):1155-1158.
[2] 陈婉珍,闫颖,吴林玲.妊娠期妇女阴道微生态研究进展[J].中国微生态学杂志,2016,28(4):489-492.
[3] 赵旭宏,徐怡嘉,侯军林.妊娠期妇女不同孕期白细胞及血小板生理变化分析[J].中国卫生检验杂志,2016,26(2):217-218.
[4] 奚伟红.不同孕期健康孕妇血脂检测的研究及临床意义[J].检验医学与临床,2017,14(A02):330-331.
[5] 仓沈元,翟光华,尹娟,等.血清铁蛋白、叶酸、维生素B-12检测对妊娠期妇女不同孕期的临床意义[J].检验医学与临床,2017,14(11):1635-1637.
[6] 周青雪,董世雷,施晓春,等.不同年龄段不同孕期孕妇体内微量元素含量的比较与分析[J].中国卫生检验杂志,2016(21):3155-3157.
[7] 石艳艳,罗红权,李宁,等.正常妊娠妇女不同孕期血常规参数变化的研究[J].检验医学与临床,2016,13(17):2442-2443.
[8] 崔贺然,全贞玉.白细胞计数及其分类与妊娠期高血压疾病的相关性研究[J].中国妇幼保健,2016,31(3):468-470.
[9] 李星,常颖,陈叙.正常孕产妇剖宫产分娩前后全血细胞参数的变化分析[J].国际妇产科学杂志,2016,43(1):32-35.
[10] 陈小燕,魏花.妊娠期贫血患者的血常规检验分析[J].中国医药导刊,2016,18(9):947-948.
[11] 邓青春,潘英连,常青,等.正常妊娠妇女临产及顺产后24h血常规检测参考区间相关研究[J].重庆医学,2016,45(5):617-618.
[12] 石中华,丁虹娟.妊娠合并血小板减少的病因及诊疗策略[J].实用妇产科杂志,2016,32(9):649-652.
[13] 杨敏,郭志伟,蒋婕.妊娠合并血小板减少症的病因分析及对母婴结局的影响[J].中国妇幼保健,2017,32(6):1155-1158.