FABPs家族基因的研究进展
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摘要
综述了脂肪酸结合蛋白(fatty acid-binding protein,FABP)的类型、分布。对肝脏型(Live fatty acid binding protein,L-FABP)、肠型(Intestinal fatty acid binding protein,I-FABP)、心脏型(Hear fatty acid binding protein,H-FABP)、脂肪细胞型(Adipocyte fatty acid binding protein,A-FABP)基因结构类型、基因多态性等相关研究进展进行了阐述,为利用FABPs基因改良和提高家畜产品数量和品质提供参考。
引文
[1]陈轶霞,骆学农,王红宁.脂肪酸结合蛋白及其生物学功能[J].生命的化学,2012(6):502-506.
[2]蒋婧.山羊PPARγ和FABP家族基因的分离鉴定、组织表达及其多态性检测[D].雅安:四川农业大学,2012.
[3]Chmurzy n'ska A.The multigene family of fatty acid-binding proteins(FABPs):function,structure and polymorphism[J].Journal of Gpplied Genetics,2006,47(1):39-48.
[4]刘顺德,李娜,高小艳,等.动物FABP家族基因与脂肪沉积关联研究进展[J].农业科学研究,2010,03:44-48.
[5]赵玉芳.Lb-FABP和L-FABP与鸡生长和体组成性状的关联及其配基结合属性研究[D].哈尔滨:东北农业大学,2013.
[6]初丽丽,王启贵,关天竹,等.I-FABP基因侧翼区多态性与鸡生长和胴体组成性状的相关研究[J].东北农业大学学报,2008(9):70-74.
[7]Gerbens F,Verburg F J,Van Moerkerk H T,et al.Association of heart and adipocyte fat acid binding protein gene expression with intramuscular fat content in pigs[J].J Anim Sci,2001,79:347-354.
[8]Michal J J,Zhang Z W,Gaskins C T,et al.The bovine fatty acid binding protein 4 gene is significantly associated with marbling andsubcutaneous fat depth in Wagyu×Limousin F2 crosses[J].Animal Genetics,2006,37(4):400-402.
[9]王启贵,关天竹,王守志,等.A-FABP基因多态性与肉鸡生长和体组成性状的关联[J].遗传,2011(2):153-162.
[10]Zimmerman A W,Veerkamp J H.New insights into the structure and function of fatty acid-binding proteins[J].Cell Mol Life Sci,2002,59(7):1096-116.
[11]杨霞.鸡Ex-FABP基因单核苷酸多态性及其与脂肪性状的相关研究[D].雅安:四川农业大学,2006.
[12]Ockner R K,Manning J A,Poppenhausen R B,et al.A binding protein for fatty acids in cytosol of intestinal mucosa,liver,myocardium,and other tissues[J].Science,1972,177(4043):56-58.
[13]王启贵.鸡FABP基因克隆、表达特性及功能研究[D].哈尔滨:东北农业大学,2004.
[14]陈桂莲.猪L-FABP基因的遗传多态性及其与肌内脂肪含量的相关性研究[D].保定:河北农业大学,2008.
[15]Gonalves F L L,Soares L M M,Figueira R L,et al.Evaluation of the expression of I-FABP and L-FABP in a necrotizing enterocolitis model after the use of Lactobacillus acidophilus[J].Journal of Pediatric Surgery,2015,50(4):543-549.
[16]Villeneuve L M,Reddy M A,Lanting L L,et al.Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes[J].PNAS,2008,105(26):9047-9052.
[17]斯琴,傅研,王旭东,等.I-FABP2基因多态性与2型糖尿病的相关性研究[J].中国医药导刊,2012(6):930-931.
[18]李文娟,李宏宾,文杰,等.鸡H-FABP和A-FABP基因表达与肌内脂肪含量相关研究[J].畜牧兽医学报,2006(5):417-423.
[19]王彦,朱庆,舒鼎铭,等.鸡H-FABP基因多态性及其与肌内脂肪含量的相关研究[J].中国畜牧杂志,2007,11:1-5.
[20]邓龙华,谢亮,罗成龙,聂庆华,张细权.鸡心脏型脂肪酸结合蛋白(H-FABP)基因多态性对肉质性状和组织表达的影响[J].农业生物技术学报,2010(3):545-555.
[21]Liang W,Zhang H L,Liu Y,et al.Investigation of the association of two candidate genes(H-FABP and PSMC1)with growth and carcass traits in Qinchuan beef cattle from China[J].Genetics and Molecular Research:GMR,2014,13(1):1876.
[22]曹健.牦牛A-FABP、H-FABP基因多态性及与胴体和肉质性状关联性分析[D].兰州:甘肃农业大学,2012.
[23]王卓,昝林森.秦川牛H-FABP基因第1外显子SNP及其与部分肉用性状相关性的研究[J].杨凌:西北农林科技大学学报(自然科学版),2008(11):11-15.
[24]李祥辉.猪的A-FABP基因遗传多态性与生产性状相关性研究[D].大庆:黑龙江八一农垦学,2010.
[25]唐红杰.陇东肉牛A-FABP和SCD1基因多态性及其与肉质性状的相关性研究[D].兰州:甘肃农业大学,2014.
[26]Uysal K T,Wiesbrock S M,Marino M W,et al.Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function[J].Nature,1997,389(6651):610-614.
[27]Kazemi M R,Mcdonald C M,Shigenaga J K,et al.Adipocyte fatty acid-binding protein expression and lipid accumulation are increased during activation of murine macrophages by toll-like receptor agonists[J].Arteriosclerosis Thrombosis&Vascular Biology,2005,25(6):1220-1224.
[28]乌仁斯琴,皇甫建,肖瑞.A-FABP与PTEN的相关性以及两者与肥胖、胰岛素抵抗的相关性研究进展[J].医学综述,2013(8):1380-1383.
[2]蒋婧.山羊PPARγ和FABP家族基因的分离鉴定、组织表达及其多态性检测[D].雅安:四川农业大学,2012.
[3]Chmurzy n'ska A.The multigene family of fatty acid-binding proteins(FABPs):function,structure and polymorphism[J].Journal of Gpplied Genetics,2006,47(1):39-48.
[4]刘顺德,李娜,高小艳,等.动物FABP家族基因与脂肪沉积关联研究进展[J].农业科学研究,2010,03:44-48.
[5]赵玉芳.Lb-FABP和L-FABP与鸡生长和体组成性状的关联及其配基结合属性研究[D].哈尔滨:东北农业大学,2013.
[6]初丽丽,王启贵,关天竹,等.I-FABP基因侧翼区多态性与鸡生长和胴体组成性状的相关研究[J].东北农业大学学报,2008(9):70-74.
[7]Gerbens F,Verburg F J,Van Moerkerk H T,et al.Association of heart and adipocyte fat acid binding protein gene expression with intramuscular fat content in pigs[J].J Anim Sci,2001,79:347-354.
[8]Michal J J,Zhang Z W,Gaskins C T,et al.The bovine fatty acid binding protein 4 gene is significantly associated with marbling andsubcutaneous fat depth in Wagyu×Limousin F2 crosses[J].Animal Genetics,2006,37(4):400-402.
[9]王启贵,关天竹,王守志,等.A-FABP基因多态性与肉鸡生长和体组成性状的关联[J].遗传,2011(2):153-162.
[10]Zimmerman A W,Veerkamp J H.New insights into the structure and function of fatty acid-binding proteins[J].Cell Mol Life Sci,2002,59(7):1096-116.
[11]杨霞.鸡Ex-FABP基因单核苷酸多态性及其与脂肪性状的相关研究[D].雅安:四川农业大学,2006.
[12]Ockner R K,Manning J A,Poppenhausen R B,et al.A binding protein for fatty acids in cytosol of intestinal mucosa,liver,myocardium,and other tissues[J].Science,1972,177(4043):56-58.
[13]王启贵.鸡FABP基因克隆、表达特性及功能研究[D].哈尔滨:东北农业大学,2004.
[14]陈桂莲.猪L-FABP基因的遗传多态性及其与肌内脂肪含量的相关性研究[D].保定:河北农业大学,2008.
[15]Gonalves F L L,Soares L M M,Figueira R L,et al.Evaluation of the expression of I-FABP and L-FABP in a necrotizing enterocolitis model after the use of Lactobacillus acidophilus[J].Journal of Pediatric Surgery,2015,50(4):543-549.
[16]Villeneuve L M,Reddy M A,Lanting L L,et al.Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes[J].PNAS,2008,105(26):9047-9052.
[17]斯琴,傅研,王旭东,等.I-FABP2基因多态性与2型糖尿病的相关性研究[J].中国医药导刊,2012(6):930-931.
[18]李文娟,李宏宾,文杰,等.鸡H-FABP和A-FABP基因表达与肌内脂肪含量相关研究[J].畜牧兽医学报,2006(5):417-423.
[19]王彦,朱庆,舒鼎铭,等.鸡H-FABP基因多态性及其与肌内脂肪含量的相关研究[J].中国畜牧杂志,2007,11:1-5.
[20]邓龙华,谢亮,罗成龙,聂庆华,张细权.鸡心脏型脂肪酸结合蛋白(H-FABP)基因多态性对肉质性状和组织表达的影响[J].农业生物技术学报,2010(3):545-555.
[21]Liang W,Zhang H L,Liu Y,et al.Investigation of the association of two candidate genes(H-FABP and PSMC1)with growth and carcass traits in Qinchuan beef cattle from China[J].Genetics and Molecular Research:GMR,2014,13(1):1876.
[22]曹健.牦牛A-FABP、H-FABP基因多态性及与胴体和肉质性状关联性分析[D].兰州:甘肃农业大学,2012.
[23]王卓,昝林森.秦川牛H-FABP基因第1外显子SNP及其与部分肉用性状相关性的研究[J].杨凌:西北农林科技大学学报(自然科学版),2008(11):11-15.
[24]李祥辉.猪的A-FABP基因遗传多态性与生产性状相关性研究[D].大庆:黑龙江八一农垦学,2010.
[25]唐红杰.陇东肉牛A-FABP和SCD1基因多态性及其与肉质性状的相关性研究[D].兰州:甘肃农业大学,2014.
[26]Uysal K T,Wiesbrock S M,Marino M W,et al.Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function[J].Nature,1997,389(6651):610-614.
[27]Kazemi M R,Mcdonald C M,Shigenaga J K,et al.Adipocyte fatty acid-binding protein expression and lipid accumulation are increased during activation of murine macrophages by toll-like receptor agonists[J].Arteriosclerosis Thrombosis&Vascular Biology,2005,25(6):1220-1224.
[28]乌仁斯琴,皇甫建,肖瑞.A-FABP与PTEN的相关性以及两者与肥胖、胰岛素抵抗的相关性研究进展[J].医学综述,2013(8):1380-1383.