针灸结合中药保留灌肠治疗溃疡性结肠炎的临床观察
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摘要
目的:观察针灸结合中药保留灌肠治疗溃疡性结肠炎的疗效。方法:将96例溃疡性结肠炎患者随机分为治疗组和对照组各48例,对照组常规应用美沙拉嗪肠溶片治疗,治疗组在对照组的基础上采用针灸结合中药保留灌肠治疗;治疗4周后观察各自近期临床疗效、电子结肠镜检查情况、Geboes指数评分、IBDQ量表评分和不良反应。结果:治疗组总有效率95. 83%,对照组总有效率81. 25%,两组比较差异有统计学意义(P <0. 05);两组治疗后电子结肠镜检查均显著改善,组间比较,差异均有统计学意义(P <0. 05);治疗组患者治疗后Geboes指数评分和IBDQ量表评分均显著优于对照组(P <0. 05);结论:针灸结合中药保留灌肠治疗溃疡性结肠炎疗效较好。
Objective To observe the efficacy of acupuncture combined with retention enema with traditional Chinese medicine in the treatment of ulcerative colitis. Methods Ninety-six patients with ulcerative colitis were randomly divided into treatment group and control group with 48 cases in each group. The control group was treated with basic treatment and oral mesalazine enteric-coated tablets( trade name: Whitney). The treatment group was based on the control group. Acupuncture and traditional Chinese medicine retention enema were used for treatment. After 4 weeks of treatment,their clinical efficacy,electronic colonoscopy status,Geboes index score,IBDQ scale score,and adverse reactions were observed. Results The total effective rate was 95. 83% in the treatment group and81. 25% in the control group. The difference between the two groups was statistically significant( P < 0. 05). After the two groups of treatment,the electronic colonoscopy was significantly improved. The differences between the two groups were compared. There was statistical significance( P < 0. 05); After treatment,Geboes index scores and IBDQ scale scores were significantly better in the treatment group than in the control group and before treatment( P < 0. 05). Conclusion Acupuncture combined Retention enema of Chinese medicine treatment of ulcerative colitis is more effective than oral mesalazine hydrochloride enteric-coated tablets.
Objective To observe the efficacy of acupuncture combined with retention enema with traditional Chinese medicine in the treatment of ulcerative colitis. Methods Ninety-six patients with ulcerative colitis were randomly divided into treatment group and control group with 48 cases in each group. The control group was treated with basic treatment and oral mesalazine enteric-coated tablets( trade name: Whitney). The treatment group was based on the control group. Acupuncture and traditional Chinese medicine retention enema were used for treatment. After 4 weeks of treatment,their clinical efficacy,electronic colonoscopy status,Geboes index score,IBDQ scale score,and adverse reactions were observed. Results The total effective rate was 95. 83% in the treatment group and81. 25% in the control group. The difference between the two groups was statistically significant( P < 0. 05). After the two groups of treatment,the electronic colonoscopy was significantly improved. The differences between the two groups were compared. There was statistical significance( P < 0. 05); After treatment,Geboes index scores and IBDQ scale scores were significantly better in the treatment group than in the control group and before treatment( P < 0. 05). Conclusion Acupuncture combined Retention enema of Chinese medicine treatment of ulcerative colitis is more effective than oral mesalazine hydrochloride enteric-coated tablets.
引文
[1]中华医学会.临床诊疗指南[M].北京:人民卫生出版社,2005:45.
[2]周仲英.中医内科学[M].北京:中国中医药出版社,2003:245-260.
[3]何兴祥,文卓夫,陈垦.循证消化病学[M].北京:清华大学出版社,2008:112-129.
[4]中国中西医结合学会消化系统疾病专业委员会.溃疡性结肠炎中西医结合诊疗指南(草案)[J].中国中西医结合消化杂志,2011,19(1):61-65.
[5]国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:48-49.
[6]中华医学会消化病学分会.对炎症性肠病诊断治疗规范的建议[J].中华消化杂志,2001,21(4):236-239.
[7]樊慧丽,陈玉梅.溃疡性结肠炎的发病机制和治疗进展[J].中国全科医学,2012,15(2):228-230.
[8]欧阳钦,胡品津,钱家鸣,等.对我国炎症性肠病诊断治疗规范的共识意见(2007年,济南)[J].中华消化杂志,2007,27(8):545-550.
[9]冯百岁,刘占举,牛正先.美沙拉秦治疗溃疡性结肠炎的临床疗效及对血清TNF-α和IL-8的影响[J].郑州大学学报(医学版),2006(05):830-833.
[10]闫军堂,赵妍,王雪茜,等.基于中医传承辅助系统的王庆国教授治疗溃疡性结肠炎用药规律研究[J].中国实验方剂学杂志,2015,21(14):186-190.
[11]田德录,田海河.慢性非特异性溃疡性结肠炎中医研究述评[J].北京中医药大学学报,1994(06):2-6+69.
[12]陈剑明,王天芳,吴秀艳,等.溃疡性结肠炎活动期和缓解期中医症状分布特点的临床调查[J].中华中医药学刊,2012,30(3):497-500.
[13]张声生.溃疡性结肠炎中医诊疗共识意见[J].中华中医药杂志,2010,25(6):891-895.
[14]沈建法,刘庆宪.溃疡性结肠炎发生的藏象学基础.中华中医药学刊,2010,28(10):2206-2208.
[15]彭楚湘,王灵,周国平,等.足三里配不同穴改善急性胃黏膜损伤作用的对比研究[J].中国针灸,2007,27(1):44-47.
[16]樊慧丽,陈玉梅.溃疡性结肠炎的发病机制和治疗进展[J].中国全科医学,2012,15(2):228-230.
[17]付学源,王真权.近5年来中药灌肠治疗溃疡性结肠炎的研究进展[J].现代中医药,2012,32(1):85-90.
[18]方晓锦,苏燕妮,黄雅慧.中药保留灌肠治疗溃疡性结肠炎36例疗效观察[J].湖南中医杂志,2013,29(11):42-43.
[2]周仲英.中医内科学[M].北京:中国中医药出版社,2003:245-260.
[3]何兴祥,文卓夫,陈垦.循证消化病学[M].北京:清华大学出版社,2008:112-129.
[4]中国中西医结合学会消化系统疾病专业委员会.溃疡性结肠炎中西医结合诊疗指南(草案)[J].中国中西医结合消化杂志,2011,19(1):61-65.
[5]国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:48-49.
[6]中华医学会消化病学分会.对炎症性肠病诊断治疗规范的建议[J].中华消化杂志,2001,21(4):236-239.
[7]樊慧丽,陈玉梅.溃疡性结肠炎的发病机制和治疗进展[J].中国全科医学,2012,15(2):228-230.
[8]欧阳钦,胡品津,钱家鸣,等.对我国炎症性肠病诊断治疗规范的共识意见(2007年,济南)[J].中华消化杂志,2007,27(8):545-550.
[9]冯百岁,刘占举,牛正先.美沙拉秦治疗溃疡性结肠炎的临床疗效及对血清TNF-α和IL-8的影响[J].郑州大学学报(医学版),2006(05):830-833.
[10]闫军堂,赵妍,王雪茜,等.基于中医传承辅助系统的王庆国教授治疗溃疡性结肠炎用药规律研究[J].中国实验方剂学杂志,2015,21(14):186-190.
[11]田德录,田海河.慢性非特异性溃疡性结肠炎中医研究述评[J].北京中医药大学学报,1994(06):2-6+69.
[12]陈剑明,王天芳,吴秀艳,等.溃疡性结肠炎活动期和缓解期中医症状分布特点的临床调查[J].中华中医药学刊,2012,30(3):497-500.
[13]张声生.溃疡性结肠炎中医诊疗共识意见[J].中华中医药杂志,2010,25(6):891-895.
[14]沈建法,刘庆宪.溃疡性结肠炎发生的藏象学基础.中华中医药学刊,2010,28(10):2206-2208.
[15]彭楚湘,王灵,周国平,等.足三里配不同穴改善急性胃黏膜损伤作用的对比研究[J].中国针灸,2007,27(1):44-47.
[16]樊慧丽,陈玉梅.溃疡性结肠炎的发病机制和治疗进展[J].中国全科医学,2012,15(2):228-230.
[17]付学源,王真权.近5年来中药灌肠治疗溃疡性结肠炎的研究进展[J].现代中医药,2012,32(1):85-90.
[18]方晓锦,苏燕妮,黄雅慧.中药保留灌肠治疗溃疡性结肠炎36例疗效观察[J].湖南中医杂志,2013,29(11):42-43.