雷火灸及寒痹方外敷联合常规西药治疗风湿寒痹型痹病25例临床观察
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摘要
目的:观察雷火灸及寒痹方外敷联合常规西药治疗风湿寒痹型痹病的临床疗效。方法:将50例风湿寒痹型痹病患者随机分为治疗组和对照组,每组25例。对照组采用常规西药治疗,治疗组在对照组治疗基础上加用雷火灸联合寒痹方外敷。2组均治疗2周。观察2组临床疗效,以及治疗前后视觉模拟评分法(VAS)评分。结果:治疗组显效12例,有效10例,无效3例,总有效率为88.00%;对照组显效8例,有效12例,无效5例,总有效率为80.00%。2组比较,差异有统计学意义(P <0.05)。治疗后7 d、14 d,2组VAS评分较治疗前均有改善(P <0.05或P <0.01),且治疗组优于对照组(P <0.05或P <0.01)。结论:雷火灸及寒痹方外敷联合常规西药治疗风湿寒痹型痹病起效快、疗效满意,值得推广运用。
Objective:To observe the clinical effect of thunder-fire moxibustion and external application of Hanbi Fang(寒痹方) combined with conventional western medicine on rheumatic-cold-bi-type bi syndrome.Methods:Fifty cases of rheumatic-cold-bi-type bi syndrome were randomly divided into a treatment group and a control group,25 cases in each group.The control group was conventionally treated with Western medicine,while the treatment group was treated with thunder-fire moxibustion combined with Hanbi Fang on the basis of the treatment for the control group.Both groups were treated for 2 weeks.The clinical efficacy and visual analogue scale(VAS)before and after treatment were observed in both groups.Results:In the treatment group,12 cases were markedly effective,10 cases were effective and 3 cases were ineffective,the total effective rate being 88.00%;while in the control group,8 cases were markedly effective,12 cases were effective and 5 cases were ineffective,the total effective rate being 80.00%.The difference between the two groups was statistically significant(P < 0.05).On the 7th and 14th days after treatment,the VAS of the two groups was improved compared with that before treatment(P < 0.05 or P < 0.01),and the treatment group was better than the control group(P < 0.05 or P < 0.01).Conclusion:Thunder-fire moxibustion and external application of Hanbi Fang combined with conventional western medicine has a quick and satisfactory curative effect in treating rheumatic-cold-bi-type bi syndrome,which is worthy of popularization and application.
Objective:To observe the clinical effect of thunder-fire moxibustion and external application of Hanbi Fang(寒痹方) combined with conventional western medicine on rheumatic-cold-bi-type bi syndrome.Methods:Fifty cases of rheumatic-cold-bi-type bi syndrome were randomly divided into a treatment group and a control group,25 cases in each group.The control group was conventionally treated with Western medicine,while the treatment group was treated with thunder-fire moxibustion combined with Hanbi Fang on the basis of the treatment for the control group.Both groups were treated for 2 weeks.The clinical efficacy and visual analogue scale(VAS)before and after treatment were observed in both groups.Results:In the treatment group,12 cases were markedly effective,10 cases were effective and 3 cases were ineffective,the total effective rate being 88.00%;while in the control group,8 cases were markedly effective,12 cases were effective and 5 cases were ineffective,the total effective rate being 80.00%.The difference between the two groups was statistically significant(P < 0.05).On the 7th and 14th days after treatment,the VAS of the two groups was improved compared with that before treatment(P < 0.05 or P < 0.01),and the treatment group was better than the control group(P < 0.05 or P < 0.01).Conclusion:Thunder-fire moxibustion and external application of Hanbi Fang combined with conventional western medicine has a quick and satisfactory curative effect in treating rheumatic-cold-bi-type bi syndrome,which is worthy of popularization and application.
引文
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[10]张梅,李龙珠,刘家军,等.威灵仙浸膏外敷联合电针齐刺法对膝关节骨性关节炎患者HA、IL-1β及MMP-1水平的影响[J].现代中西医结合杂志,2015,24(32):3556-3558,3561.
[11]赵宝祥,孙丙银,邹季.复方威灵仙熏洗联合臭氧关节腔内注射治疗老年膝骨关节炎临床疗效研究[J].风湿病与关节炎,2015,4(7):18-21.
[2]中华医学会风湿病学分会.骨关节炎诊断与治疗指南[J].中华风湿病学杂志,2010,14(6):416-419.
[3]HANNONEN P,M?TT?NEN T,OKA M.Palindromic rheumatism Aclinical survery of sixty patients[J].Scand J Rheumatol,1987,16(6):413-420.
[4]张伯礼,吴勉华.中医内科学[M].北京:中国中医药出版社,2017:366.
[5]ZHANG SN,OUYANG LZ,WANG XZ,et al.Effec of acupuncture plus thunder-fire moxibustion on MMP-3,TIMP-1 and TGF-β1 in rats with knee osteoarthritis[J].Journal of Acupuncture and Tuina Science,2017,15(5):322-327.
[6]林平冬,翁霞萍,刘发元,等.牛膝有效成分防治骨关节炎的作用机制探讨[J].风湿病与关节炎,2015,4(2):56-59.
[7]陈琼,赵明才,陈悦,等.姜黄素对骨关节炎软骨细胞增殖及分泌MMP-13,IL-6的影响[J].现代中西医结合杂志,2013,22(5):459-461.
[8]蔡辉,刘春丽,赵智明.姜黄素治疗类风湿关节炎机制研究进展[J].山东医药,2015,55(4):100-104.
[9]邓龙飞,汪永忠,韩燕全,等.威灵仙总皂苷抑制佐剂性关节炎大鼠JAK2/STAT3信号通路[J].细胞与分子免疫学杂志,2015,31(2):153-158.
[10]张梅,李龙珠,刘家军,等.威灵仙浸膏外敷联合电针齐刺法对膝关节骨性关节炎患者HA、IL-1β及MMP-1水平的影响[J].现代中西医结合杂志,2015,24(32):3556-3558,3561.
[11]赵宝祥,孙丙银,邹季.复方威灵仙熏洗联合臭氧关节腔内注射治疗老年膝骨关节炎临床疗效研究[J].风湿病与关节炎,2015,4(7):18-21.