预防用药对自发性气胸胸腔闭式引流术后患者疗效观察
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摘要
目的观察预防用抗生素治疗对自发性气胸胸腔闭式引流术术后患者的疗效。方法收集2015年5月-2017年5月胸外科自发性气胸行胸腔闭式引流术的患者90例,选择使用抗生素治疗的患者50例为暴露组,未采用抗生素治疗的患者40例为非暴露组。比较2组患者手术情况(住院时间、置管时间、胸腔引流)及术后感染发生情况。结果 2组患者住院时间、胸腔引流量、置管时间及术后感染发生率比较差异均无统计学意义(P>0.05)。结论抗生素对自发性气胸胸腔闭式引流术后患者感染无影响,自发性气胸患者胸腔闭式引流术后不必常规应用抗生素,应严格掌握抗生素用药指征。
Objective To observe the effect of prophylactic antibiotics on controlling of infection following tube thoracostomy for spontaneous pneumothorax.Methods A total of 90 patients with spontaneous pneumothorax who received closed tube drainage from May 2015 to May 2017 were collected.50 patients who were treated with antibiotics were selected as exposure group,40 patients who were not treated with antibiotics were non-exposed group.The operation status(hospitalization time,catheterization time,chest drainage)and postoperative infection were compared between the two groups.Results There were no significant differences in the length of hospital stay,chest drainage,catheterization time and postoperative infection between the two groups(P>0.05).Conclusion The use of antibiotics does not appear to reduce the risk of infection following the closed tube thoracostomy for spontaneous pneumothorax,the prophylactic antibiotics are not routine used for patients following closed tube thoracostomy for spontaneous pneumothorax and should be strictly controlled.
Objective To observe the effect of prophylactic antibiotics on controlling of infection following tube thoracostomy for spontaneous pneumothorax.Methods A total of 90 patients with spontaneous pneumothorax who received closed tube drainage from May 2015 to May 2017 were collected.50 patients who were treated with antibiotics were selected as exposure group,40 patients who were not treated with antibiotics were non-exposed group.The operation status(hospitalization time,catheterization time,chest drainage)and postoperative infection were compared between the two groups.Results There were no significant differences in the length of hospital stay,chest drainage,catheterization time and postoperative infection between the two groups(P>0.05).Conclusion The use of antibiotics does not appear to reduce the risk of infection following the closed tube thoracostomy for spontaneous pneumothorax,the prophylactic antibiotics are not routine used for patients following closed tube thoracostomy for spontaneous pneumothorax and should be strictly controlled.
引文
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[8] Bosman A,de Jong MB,Debij J,et al.Systematic review and meta-analysis of antibiotic prophylaxis to prevent infections from chest drains in blunt and penetrating thoracic injuries[J].Br J Surg,2012,99(4):506-513.DOI:10.1002/bjs.7744.
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[10] 麻日虎,李莹.预防用药对控制胸部创伤后胸腔闭式引流术后感染的影响[J].中国现代医生,2013,51(4):144-145.
[11] 宴丽云,周灵云,葛小琴,等.预防用药对控制胸部创伤患者胸腔闭式引流术后感染的影响[J].中华医院感染学杂志,2015,25(12):2743-2744,2792.DOI:10.11816/cn.ni.2015-141443.
[2] 王朝,邹卫.原发性自发性气胸病因研究进展[J].临床肺科杂志,2015,20(6):1120-1124.DOI:10.3969/j.issn.1009-6663.2015.06.049.
[3] 宋国强.林彬.卢火佺,等.胸腔闭式引流在自发性气胸治疗中的研究进展[J].中国现代医生,2017,55(6):164-168.
[4] Heydari MB,Hessami MA,Setayeshi K,et al.Use of prophylactic antibiotics following tube thoracostomy for blunt chest trauma in the prevention of empyema and pneumonia[J].J Inj Violence Res,2014,6(2):91-92.DOI:10.5249/jivr.v6i2.11.
[5] Choi WI.Pneumothorax[J].Tuberc Respir Dis (Seoul),2014,76(3):99-104.DOI:10.4046/trd.2014.76.3.99.
[6] Helling TS,Gyles NR,Eisenstein CL,et al.Complications following blunt and penetrating injuries in 216 victims of chest trauma requiring tube thoracostomy[J].J Trauma,1989,29(10):1367-1370.
[7] Luchette FA,Barrie PS,Oswanski MF,et al.Practice management guidelines for prophylactic antibiotic use in tube thoracostomy for traumatic hemopneumothorax:the EAST Practice Management Guidelines Work Group.Eastern Association for Trauma[J].J Trauma,2000,48(4):735-757.
[8] Bosman A,de Jong MB,Debij J,et al.Systematic review and meta-analysis of antibiotic prophylaxis to prevent infections from chest drains in blunt and penetrating thoracic injuries[J].Br J Surg,2012,99(4):506-513.DOI:10.1002/bjs.7744.
[9] 何春雷.预防用药对控制胸部创伤后胸腔闭式引流术后感染的影响[J].中国医药指南,2014,12(22):187-188.DOI:10.15912/j.cnki.gocm.2014.22.197.
[10] 麻日虎,李莹.预防用药对控制胸部创伤后胸腔闭式引流术后感染的影响[J].中国现代医生,2013,51(4):144-145.
[11] 宴丽云,周灵云,葛小琴,等.预防用药对控制胸部创伤患者胸腔闭式引流术后感染的影响[J].中华医院感染学杂志,2015,25(12):2743-2744,2792.DOI:10.11816/cn.ni.2015-141443.