王祖龙治疗死精子症用药规律分析
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摘要
目的:总结王祖龙治疗死精子症的用药经验。方法:收集2015年4月至2017年4月就诊于河南省中医院中西医结合生殖男科门诊的死精子症患者380例,建立Epidata3. 0软件数据库,将每一味药作为一个统计变量,药物按有=1,无=0赋值,采用频率、频数以及聚类分析方法进行分析研究。结果:41味中药使用频率> 10%;聚类分析法将药物分为补阳药、补阴药、补气药、补血药、行气活血药、健脾化湿药、益肾固精药、清热药8大类。结论:王祖龙治疗死精子症,或阴阳并补,或气血双补,或补血与活血并施,或健脾化湿类与益肾固精类同用,或配伍清热类药物。
Objective: To summarize Wang Zu-long' s drug-use experience of treating dead spermatozoa. Methods: Three hundred and eighty patients with dead spermatozoa who were treated in the Outpatient Department of Reproductive Andrology of Integrated Traditional and Western Medicine of Henan Provincial Hospital of CM from April 2015 to April 2017 were collected. The software database of Epidata 3. 0 was established. Each drug was regarded as a statistical variable,and the drug was assigned as having =1 and not = 0. The frequency rate,frequency number and cluster analysis were used to analyze and study. Results: The frequency of 41 kinds of Chinese herbal medicines was more than 10%. Cluster analysis classified the medicines into 8 categories: yang-tonifying drugs,yin-tonifying drugs,qi-tonifying drugs,blood-tonifying drugs,qi-activating and blood-circulation-promoting drugs,spleen-strengthening and dampness-removing drugs,kidney-tonifying and essence-strengthening drugs,and heat-clearing drugs.Conclusion: In treating dead spermatozoa,Professor Wang Zu-long uses the following methods: nourishing both yin and yang,or nourishing both qi and blood,or nourishing blood and promoting blood circulation together,or using spleen-strengthening and dampness-removing drugs,and kidney-tonifying and essence-strengthening drugs together,or combined with heat-clearing drugs.
Objective: To summarize Wang Zu-long' s drug-use experience of treating dead spermatozoa. Methods: Three hundred and eighty patients with dead spermatozoa who were treated in the Outpatient Department of Reproductive Andrology of Integrated Traditional and Western Medicine of Henan Provincial Hospital of CM from April 2015 to April 2017 were collected. The software database of Epidata 3. 0 was established. Each drug was regarded as a statistical variable,and the drug was assigned as having =1 and not = 0. The frequency rate,frequency number and cluster analysis were used to analyze and study. Results: The frequency of 41 kinds of Chinese herbal medicines was more than 10%. Cluster analysis classified the medicines into 8 categories: yang-tonifying drugs,yin-tonifying drugs,qi-tonifying drugs,blood-tonifying drugs,qi-activating and blood-circulation-promoting drugs,spleen-strengthening and dampness-removing drugs,kidney-tonifying and essence-strengthening drugs,and heat-clearing drugs.Conclusion: In treating dead spermatozoa,Professor Wang Zu-long uses the following methods: nourishing both yin and yang,or nourishing both qi and blood,or nourishing blood and promoting blood circulation together,or using spleen-strengthening and dampness-removing drugs,and kidney-tonifying and essence-strengthening drugs together,or combined with heat-clearing drugs.
引文
[1]世界卫生组织.世界卫生组织男性不育标准化检查与诊疗手册[M].北京:人民卫生出版社,2007:146.
[2]世界卫生组织. WHO人类精液检查与处理实验室手册[M]. 5版.北京:人民卫生出版社,2011:99.
[3]郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:103.
[4]秦国政.中医男科学[M].北京:中国中医药出版社,2012:203-206.
[5] COOPER TG,NOONAN E,VON ECKARDSTEIN S,et al. WorldHealth Organization reference values for human semen characteris-tics[J]. Hum Reprod Update,2000,16(3):231-245.
[6]谢秀萍. 852例男性不育患者精液常规分析[J].齐齐哈尔医学院学报,2005,26(5):506-507.
[7]贾金铭,马卫国.中西医结合治疗男性不育症的思路[J].中国男科学杂志,2006,20(7):1-2.
[8]孔舒,孙筱放,郑育红,等.少弱精子症、死精子症、无精子症患者细胞遗传学分析[J].中国优生与遗传杂志,2012,20(7):51-52.
[9]粟高国.男性饮酒导致继发性死精不孕的治疗探讨[J].中国医药导报,2008,5(27):71.
[10]孙自学.实用中西医诊疗男科学[M].呼和浩特:内蒙古大学出版社,2003:466-478.
[11]王洪军,冯立,褚征,等.人参多糖对冷应激大鼠睾丸雄激素受体mRNA表达及血浆睾酮的影响[J].时珍国医国药,2008,19(4):929-930.
[12]李笑甜,宋忠臣.补骨脂及其活性成分免疫调节作用研究进展[J].现代免疫学,2017,37(1):80-83.
[13]刘忠平,李质馨,李守远,等.淫羊藿对生殖系统影响研究进展[J].中国妇幼保健,2013,28(5):884-886.
[2]世界卫生组织. WHO人类精液检查与处理实验室手册[M]. 5版.北京:人民卫生出版社,2011:99.
[3]郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:103.
[4]秦国政.中医男科学[M].北京:中国中医药出版社,2012:203-206.
[5] COOPER TG,NOONAN E,VON ECKARDSTEIN S,et al. WorldHealth Organization reference values for human semen characteris-tics[J]. Hum Reprod Update,2000,16(3):231-245.
[6]谢秀萍. 852例男性不育患者精液常规分析[J].齐齐哈尔医学院学报,2005,26(5):506-507.
[7]贾金铭,马卫国.中西医结合治疗男性不育症的思路[J].中国男科学杂志,2006,20(7):1-2.
[8]孔舒,孙筱放,郑育红,等.少弱精子症、死精子症、无精子症患者细胞遗传学分析[J].中国优生与遗传杂志,2012,20(7):51-52.
[9]粟高国.男性饮酒导致继发性死精不孕的治疗探讨[J].中国医药导报,2008,5(27):71.
[10]孙自学.实用中西医诊疗男科学[M].呼和浩特:内蒙古大学出版社,2003:466-478.
[11]王洪军,冯立,褚征,等.人参多糖对冷应激大鼠睾丸雄激素受体mRNA表达及血浆睾酮的影响[J].时珍国医国药,2008,19(4):929-930.
[12]李笑甜,宋忠臣.补骨脂及其活性成分免疫调节作用研究进展[J].现代免疫学,2017,37(1):80-83.
[13]刘忠平,李质馨,李守远,等.淫羊藿对生殖系统影响研究进展[J].中国妇幼保健,2013,28(5):884-886.