血清PG检测在胃癌早期筛查及术后监测中的应用
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摘要
目的:探讨血清PG检测在胃癌早期筛查及术后监测中的应用价值。方法:选取笔者所在医院2016年5月-2017年5月收治的胃癌患者86例,行全胃切除术者29例,为胃癌全胃切除术组,同时选取同期于笔者所在医院进行体检的健康人82例作为对照组,以胶乳免疫比浊法对所有患者血清PG含量进行检测,并对比检测结果。结果:胃癌患者血清PGⅠ含量和PGⅠ/PGⅡ比值远低于健康对照组,差异均有统计学意义(P<0.05);胃癌全胃切除术组患者血清PGⅠ、PGⅡ含量远低于胃癌组患者,差异有统计学意义(P<0.05);术后复发组患者血清PGⅠ、PGⅡ含量远高于术后未复发组患者,差异有统计学意义(P<0.05)。结论:血清PG检测对胃癌早期筛查具一定指导作用,同时也可对胃癌术后复发情况进行监测,具较高应用价值。
Objective:To explore the value of serum PG detection in early screening and postoperative monitoring of gastric cancer.Method:86 cases of gastric cancer treated by our hospital from May 2016 to May 2017 were selected,at the same time, the healthy people who had the same time in our hospital were selected as the control group,the serum PG content of all patients was detected with the latex immunity and turbidity method, and the results were compared.Result:Gastric cancer patients with total gastrectomy group serum PG Ⅰ, PG Ⅱ content is far lower than the patients with gastric cancer group, Statistical significance(P<0.05);The difference between statistical significance(P<0.05); Postoperative recurrence patients serum PG Ⅰ, PG Ⅱ content is much higher than the group of patients, no postoperative recurrence statistical significance difference(P<0.05).Conclusion:The serum PG test can guide the early screening of gastric cancer, and it can also be used to monitor the recurrence of gastric cancer.
Objective:To explore the value of serum PG detection in early screening and postoperative monitoring of gastric cancer.Method:86 cases of gastric cancer treated by our hospital from May 2016 to May 2017 were selected,at the same time, the healthy people who had the same time in our hospital were selected as the control group,the serum PG content of all patients was detected with the latex immunity and turbidity method, and the results were compared.Result:Gastric cancer patients with total gastrectomy group serum PG Ⅰ, PG Ⅱ content is far lower than the patients with gastric cancer group, Statistical significance(P<0.05);The difference between statistical significance(P<0.05); Postoperative recurrence patients serum PG Ⅰ, PG Ⅱ content is much higher than the group of patients, no postoperative recurrence statistical significance difference(P<0.05).Conclusion:The serum PG test can guide the early screening of gastric cancer, and it can also be used to monitor the recurrence of gastric cancer.
引文
[1]石贞玉,厉永强,吴铭,等.血清PG检测在胃癌早期筛查及术后监测中的应用[J].河南大学学报:医学版,2014,33(3):188-189,194.
[2]康运凯,吴学炜,史小芹,等.七项血清标志物在胃癌患者术前术后检测的临床意义[J].中华检验医学杂志,2017,40(1):60-63.
[3]汪畅,王凤超.血清胃蛋白酶原检测及其在胃癌筛查中的应用进展[J].中华全科医学,2013,11(8):1280-1281.
[4]吴寿荣.慢性萎缩性胃炎患者血清胃蛋白酶原检测的临床意义[J].中国老年学杂志,2013,33(20):5142-5143.
[5]朱俊,彭光秀.血清胃蛋白酶原检测在胃黏膜疾病中的意义[J].中国保健营养,2016,26(20):104-105.
[6]乐嫣,项明洁,张华,等.血清胃蛋白酶原检测在胃相关疾病中的诊断价值[J].标记免疫分析与临床,2016,23(1):12-14.
[7]俞瑾,吕宾,黄晨,等.血清胃蛋白酶原检测对胃癌和慢性胃炎的意义[J].中国医师进修杂志,2016,39(4):321-324.
[8]徐巧莲,万小勇,杜燕,等.血清胃蛋白酶原检测在胃癌筛查中的价值[J].胃肠病学,2012,17(10):614-617.
[9]葛洋,王华,赵绍林,等.胃镜联合血清胃蛋白酶原检测在胃癌诊断中的意义[J].中外医学研究,2016,14(36):50-50,51.
[10]史玲玲,张英波,董林,等.胃癌早期诊断中血清胃蛋白酶原检测的应用价值[J].中国实用医药,2014,9(26):22-23.
[11]梁艳丽,李凤,王欣,等.血清胃蛋白酶原检测在胃部疾病诊断中的临床意义[J].临床医药实践,2016,25(8):594-596.
[12]邱宏毅,颜秀娟,陈胜良,等.血清胃蛋白酶原检测在胃癌预警和胃黏膜功能评价中的价值[J].胃肠病学,2015,20(10):625-628.
[13]赵丽华,何谦,张磊,等.血清PGⅠ、PGⅡ与CEA、CA72-4联合检测对胃癌的诊断价值[J].现代肿瘤医学,2013,21(10):2283-2286.
[14]陆明洁.血清PGⅠ、PGⅡ、PGⅠ/PGⅡ比值、癌胚抗原(CEA)、CA19-9、CA72-4检测对胃癌的诊断意义分析[J].医药,2016(6):16.
[15]黄道桂,任传路,虞红艳,等.血清PGⅠ,PGⅡ,TK1,TSGF,CEA与CA724联合检测在胃癌诊断中的应用价值[J].现代检验医学杂志,2015(1):101-104.
[2]康运凯,吴学炜,史小芹,等.七项血清标志物在胃癌患者术前术后检测的临床意义[J].中华检验医学杂志,2017,40(1):60-63.
[3]汪畅,王凤超.血清胃蛋白酶原检测及其在胃癌筛查中的应用进展[J].中华全科医学,2013,11(8):1280-1281.
[4]吴寿荣.慢性萎缩性胃炎患者血清胃蛋白酶原检测的临床意义[J].中国老年学杂志,2013,33(20):5142-5143.
[5]朱俊,彭光秀.血清胃蛋白酶原检测在胃黏膜疾病中的意义[J].中国保健营养,2016,26(20):104-105.
[6]乐嫣,项明洁,张华,等.血清胃蛋白酶原检测在胃相关疾病中的诊断价值[J].标记免疫分析与临床,2016,23(1):12-14.
[7]俞瑾,吕宾,黄晨,等.血清胃蛋白酶原检测对胃癌和慢性胃炎的意义[J].中国医师进修杂志,2016,39(4):321-324.
[8]徐巧莲,万小勇,杜燕,等.血清胃蛋白酶原检测在胃癌筛查中的价值[J].胃肠病学,2012,17(10):614-617.
[9]葛洋,王华,赵绍林,等.胃镜联合血清胃蛋白酶原检测在胃癌诊断中的意义[J].中外医学研究,2016,14(36):50-50,51.
[10]史玲玲,张英波,董林,等.胃癌早期诊断中血清胃蛋白酶原检测的应用价值[J].中国实用医药,2014,9(26):22-23.
[11]梁艳丽,李凤,王欣,等.血清胃蛋白酶原检测在胃部疾病诊断中的临床意义[J].临床医药实践,2016,25(8):594-596.
[12]邱宏毅,颜秀娟,陈胜良,等.血清胃蛋白酶原检测在胃癌预警和胃黏膜功能评价中的价值[J].胃肠病学,2015,20(10):625-628.
[13]赵丽华,何谦,张磊,等.血清PGⅠ、PGⅡ与CEA、CA72-4联合检测对胃癌的诊断价值[J].现代肿瘤医学,2013,21(10):2283-2286.
[14]陆明洁.血清PGⅠ、PGⅡ、PGⅠ/PGⅡ比值、癌胚抗原(CEA)、CA19-9、CA72-4检测对胃癌的诊断意义分析[J].医药,2016(6):16.
[15]黄道桂,任传路,虞红艳,等.血清PGⅠ,PGⅡ,TK1,TSGF,CEA与CA724联合检测在胃癌诊断中的应用价值[J].现代检验医学杂志,2015(1):101-104.