分子印迹技术在电化学中的应用
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摘要
分子印迹技术是一种对目标分子进行特异性识别的新技术。分子印迹聚合物具有制备方法简单、稳定性好、识别能力强等特点,这些特点使其在膜分离、固相萃取、传感器、催化等方面有了广泛的应用。总结归纳了分子印迹技术的主要特点、分子印迹电化学传感器的制备方法和类别,并对未来发展趋势进行了展望。
Molecular imprinting technology is a new technique which can recognize target molecules.Molecular imprinted polymers have been widely used in membrane separation,solid phase extraction,sensor and catalysis because of the advantages including simple preparation method,good stability and strong recognition ability.The characteristics of molecular imprinting techniques and the methods & types of molecular imprinting electrochemical sensors were summarized.
Molecular imprinting technology is a new technique which can recognize target molecules.Molecular imprinted polymers have been widely used in membrane separation,solid phase extraction,sensor and catalysis because of the advantages including simple preparation method,good stability and strong recognition ability.The characteristics of molecular imprinting techniques and the methods & types of molecular imprinting electrochemical sensors were summarized.
引文
[1]尚宏周,梁红玉,张小梅,等.分子印迹聚合物的最新研究进展[J].现代化工,2013,33(12):28-30.
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[8]Sellergren B,Allender C J.Molecularly imprinted polymers:a bridge to advanced drug delivery[J].Advanced Drug Delivery Reviews,2005,57(12):1733-1741.
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[11]Lian W,Liu S,Yu J,et al.Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin[J].Biosensors&Bioelectronics,2012,38(1):163-169.
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[16]Nezhadali A,Pirayesh S,Shadmehri R.Computer-assisted sensor design and analysis of 2-aminobenzimidazole in biological model samples based on electropolymerized-molecularly imprinted polypyrrole modified pencil graphite electrode[J].Sensors&Actuators B Chemical,2013,185(8):17-23.
[17]Guo Z Z,Florea A,Cristea C,et al.1,3,5-Trinitrotoluene detection by a molecularly imprinted polymer sensor based on electropolymerization of a microporous-metal-organic framework[J].Sensors&Actuators B Chemical,2015,207:960-966.
[18]Zhang J,Niu Y,Li S,et al.A molecularly imprinted electrochemical sensor based on sol-gel technology and multiwalled carbon nanotubes-nafion functional layer for determination of2-nonylphenol in environmental samples[J].Sensors&Actuators B Chemical,2014,193(3):844-850.
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[21]Rao H,Chen M,Ge H,et al.A novel electrochemical sensor based on Au@PANI composites film modified glassy carbon electrode binding molecular imprinting technique for the determination of melamine[J].Biosensors&Bioelectronics,2017,87:1029-1035.
[22]Widayani,Yanti,Wungu T D K,et al.Preliminary study of molecularly imprinted polymer-based potentiometric sensor for glucose[J].Procedia Engineering,2017,170:84-87.
[23]Smolinska-Kempisty K,Ahmad O S,Guerreiro A,et al.New potentiometric sensor based on molecularly imprinted nanoparticles for cocaine detection[J].Biosensors&Bioelectronics,2017,96:49-54.
[24]Graniczkowska K,Pütz M,Hauser F M,et al.Capacitive sensing of N-formylamphetamine based on immobilized molecular imprinted polymers[J].Biosensors&Bioelectronics,2017,92:741-747.
[25]Idil N,Hedstr9m M,Denizli A,et al.Whole cell based microcontact imprinted capacitive biosensor for the detection of escherichia coli[J].Biosensors&Bioelectronics,2016,87:807-815.
[26]Xue C,Han Q,Wang Y,et al.Amperometric detection of dopamine in human serum by electrochemical sensor based on gold nanoparticles doped molecularly imprinted polymers[J].Biosensors&Bioelectronics,2013,49(22):199-203.
[27]Zhao H,Wang H,Quan X,et al.Amperometric sensor for tetracycline determination based on molecularly imprinted technique[J].Procedia Environmental Sciences,2013,18:249-257.
[28]Chen H,Zhang Z,Cai R,et al.Molecularly imprinted electrochemical sensor based on nickel nanoparticles-graphene nanocomposites modified electrode for determination of tetrabromobisphenol A[J].Electrochimica Acta,2014,117(4):385-392.
[29]Suedee R,Intakong W,Dickert F L.Molecularly imprinted polymer-modified electrode for on-line conductometric monitoring of haloacetic acids in chlorinated water[J].Analytica Chimica Acta,2006,569(1):66-75.
[30]Chai C,Liu G,Feng L,et al.Towards the development of a portable sensor based on a molecularly imprinted membrane for the rapid determination of salbutamol in pig urine[J].Analytica Chimica Acta,2010,675(2):185-190.
[2]尚宏周,赵敬东,何俊男,等.离子印迹聚合物的最新研究进展[J].现代化工,2016,36(9):32-35.
[3]Cai D,Ren L,Zhao H,et al.A molecular-imprint nanosensor for ultrasensitive detection of proteins[J].Nature Nanotechnology,2010,5(8):597-601.
[4]Li X,Zhang L,Wei X,et al.A sensitive and renewable chlortoluron molecularly imprinted polymer sensor based on the gate-controlled catalytic electrooxidation of H2O2on magnetic Nano-NiO[J].Electroanalysis,2013,25(25):1286-1293.
[6]Lee D S,Song H W,Choi C G,et al.Pore-size reduction protocol for SiN membrane nanopore using the thermal reflow in nanoimprinting for nanobio-based sensing[J].Journal of Biomedical Optics,2014,19(5):466-469.
[7]Ribeiro A,Veiga F,Santos D,et al.Bioinspired imprinted PHEMA-hydrogels for ocular delivery of carbonic anhydrase inhibitor drugs[J].Biomacromolecules,2011,12(3):701-709.
[8]Sellergren B,Allender C J.Molecularly imprinted polymers:a bridge to advanced drug delivery[J].Advanced Drug Delivery Reviews,2005,57(12):1733-1741.
[9]Huang B Y,Chen Y C,Wang G R,et al.Preparation and evaluation of a monolithic molecularly imprinted polymer for the chiral separation of neurotransmitters and their analogues by capillary electrochromatography[J].Journal of Chromatography A,2011,1218(6):849-855.
[10]易娜,张教强,史长明,等.分子印迹传感器的研究进展[J].材料开发与应用,2013,28(1):117-124.
[11]Lian W,Liu S,Yu J,et al.Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin[J].Biosensors&Bioelectronics,2012,38(1):163-169.
[12]Santos W D J R,Santhiago M,Yoshida I V P,et al.Electrochemical sensor based on imprinted sol-gel and nanomaterial for determination of caffeine[J].Sensors&Actuators BChemical,2012,166-167(6):739-745.
[13]Zhang M,Zhao H T,Xie T J,et al.Molecularly imprinted polymer on graphene surface for selective and sensitive electrochemical sensing imidacloprid[J].Sensors&Actuators BChemical,2017,252:991-1002.
[14]Ma Y,Shen X L,Zeng Q,et al.A multi-walled carbon nanotubes based molecularly imprinted polymers electrochemical sensor for the sensitive determination of HIV-p24[J].Talanta,2017,164:121-127.
[15]Yang H,Li L,Ding Y,et al.Molecularly imprinted electrochemical sensor based on bioinspired Au microflowers for ultra-trace cholesterol assay[J].Biosensors&Bioelectronics,2017,92:748-754.
[16]Nezhadali A,Pirayesh S,Shadmehri R.Computer-assisted sensor design and analysis of 2-aminobenzimidazole in biological model samples based on electropolymerized-molecularly imprinted polypyrrole modified pencil graphite electrode[J].Sensors&Actuators B Chemical,2013,185(8):17-23.
[17]Guo Z Z,Florea A,Cristea C,et al.1,3,5-Trinitrotoluene detection by a molecularly imprinted polymer sensor based on electropolymerization of a microporous-metal-organic framework[J].Sensors&Actuators B Chemical,2015,207:960-966.
[18]Zhang J,Niu Y,Li S,et al.A molecularly imprinted electrochemical sensor based on sol-gel technology and multiwalled carbon nanotubes-nafion functional layer for determination of2-nonylphenol in environmental samples[J].Sensors&Actuators B Chemical,2014,193(3):844-850.
[19]Zhou T,Feng Y,Zhou L,et al.Selective and sensitive detection of tetrabromobisphenol-a in water samples by molecularly imprinted electrochemical sensor[J].Sensors&Actuators B Chemical,2016,236:153-162.
[20]Toro M J U,Marestoni L D,Sotomayor M D P T.A new biomimetic sensor based on molecularly imprinted polymers for highly sensitive and selective determination of hexazinone herbicide[J].Sensors&Actuators B Chemical,2015,208:299-306.
[21]Rao H,Chen M,Ge H,et al.A novel electrochemical sensor based on Au@PANI composites film modified glassy carbon electrode binding molecular imprinting technique for the determination of melamine[J].Biosensors&Bioelectronics,2017,87:1029-1035.
[22]Widayani,Yanti,Wungu T D K,et al.Preliminary study of molecularly imprinted polymer-based potentiometric sensor for glucose[J].Procedia Engineering,2017,170:84-87.
[23]Smolinska-Kempisty K,Ahmad O S,Guerreiro A,et al.New potentiometric sensor based on molecularly imprinted nanoparticles for cocaine detection[J].Biosensors&Bioelectronics,2017,96:49-54.
[24]Graniczkowska K,Pütz M,Hauser F M,et al.Capacitive sensing of N-formylamphetamine based on immobilized molecular imprinted polymers[J].Biosensors&Bioelectronics,2017,92:741-747.
[25]Idil N,Hedstr9m M,Denizli A,et al.Whole cell based microcontact imprinted capacitive biosensor for the detection of escherichia coli[J].Biosensors&Bioelectronics,2016,87:807-815.
[26]Xue C,Han Q,Wang Y,et al.Amperometric detection of dopamine in human serum by electrochemical sensor based on gold nanoparticles doped molecularly imprinted polymers[J].Biosensors&Bioelectronics,2013,49(22):199-203.
[27]Zhao H,Wang H,Quan X,et al.Amperometric sensor for tetracycline determination based on molecularly imprinted technique[J].Procedia Environmental Sciences,2013,18:249-257.
[28]Chen H,Zhang Z,Cai R,et al.Molecularly imprinted electrochemical sensor based on nickel nanoparticles-graphene nanocomposites modified electrode for determination of tetrabromobisphenol A[J].Electrochimica Acta,2014,117(4):385-392.
[29]Suedee R,Intakong W,Dickert F L.Molecularly imprinted polymer-modified electrode for on-line conductometric monitoring of haloacetic acids in chlorinated water[J].Analytica Chimica Acta,2006,569(1):66-75.
[30]Chai C,Liu G,Feng L,et al.Towards the development of a portable sensor based on a molecularly imprinted membrane for the rapid determination of salbutamol in pig urine[J].Analytica Chimica Acta,2010,675(2):185-190.