腹腔镜下病灶切除联合曼月乐治疗子宫腺肌病的临床效果
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摘要
目的探讨腹腔镜下病灶切除联合曼月乐治疗子宫腺肌病的临床效果。方法回顾性分析2012年2月~2013年4月我院收入行腹腔镜下子宫腺肌病病灶切除的患者66例,根据其采用的治疗方式分为对照组、联合组,对照组(30例)采用单纯病灶切除手术治疗,联合组(36例)在病灶切除的基础上加用曼月乐,比较两组患者术前术后的痛经、月经周期、经期、经量等情况及两组的不良反应发生率。结果两组患者术前的痛经视觉模拟评分、月经周期、经期、经量差异无统计学意义(P>0.05);联合组患者的术后12、24个月的痛经视觉模拟评分及术后24个月的经期、经量与同期对照组差异有统计学意义(P<0.05)。结论腹腔镜下子宫腺肌病病灶切除术联合曼月乐治疗子宫腺肌病的临床效果较理想,值得临床优先考虑选用。
Objective To discuss the clinical effect of laparoscopic lesionectomy combined with Mirena in treatment of adenomyosis. Methods 66 patients with adenomyosis receiving laparoscopic lesionectomy in our hospital from February2012 to April 2013 were retrospectively analyzed and divided into control group and combination group according to the method of treatment.30 patients in control group were treated by simple lesionectomy,while the 36 patients in combination group were treated by lesionectomy plus Mirena.The condition of dysmenorrheal,menstrual cycle,menstrual period,menstrual volume before and after operation in patients between two groups and incidence rate of adverse reaction between two groups was compared respectively. Results There was no statistical difference of visual analogue scale for dysmenorrhea,menstrual cycle,menstrual period,menstrual volume before operation between two groups(P>0.05).There was a statistical difference of visual analogue scale for dysmenorrhea after 12,24 months and menstrual period,menstrual volume after 24 months in patients of combination group compared with that of control group at the same period(P<0.05). Conclusion The clinical effect of laparoscopic lesionectomy combined with Mirena is favorable in treatment of adenomyosis,which is worthy to be considered as a preferred method in clinic.
Objective To discuss the clinical effect of laparoscopic lesionectomy combined with Mirena in treatment of adenomyosis. Methods 66 patients with adenomyosis receiving laparoscopic lesionectomy in our hospital from February2012 to April 2013 were retrospectively analyzed and divided into control group and combination group according to the method of treatment.30 patients in control group were treated by simple lesionectomy,while the 36 patients in combination group were treated by lesionectomy plus Mirena.The condition of dysmenorrheal,menstrual cycle,menstrual period,menstrual volume before and after operation in patients between two groups and incidence rate of adverse reaction between two groups was compared respectively. Results There was no statistical difference of visual analogue scale for dysmenorrhea,menstrual cycle,menstrual period,menstrual volume before operation between two groups(P>0.05).There was a statistical difference of visual analogue scale for dysmenorrhea after 12,24 months and menstrual period,menstrual volume after 24 months in patients of combination group compared with that of control group at the same period(P<0.05). Conclusion The clinical effect of laparoscopic lesionectomy combined with Mirena is favorable in treatment of adenomyosis,which is worthy to be considered as a preferred method in clinic.
引文
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[14]赵惠杰.曼月乐对不愿手术的子宫内膜异位症患者的疗效观察[J].中国当代医药,2014,21(8):177-179.
[15]张彭南,朱杰,薛晓红.腹腔镜下子宫腺肌病病灶切除术治疗子宫腺肌病的临床分析[J].现代妇产科进展,2015,24(2):135-137.
[2]黄晶,徐娟,李雪年,等.宫腔镜电切术治疗子宫黏膜下肌瘤的临床观察[J].江西医药,2013,48(7):613-615.
[3]刘海燕,陶李苏,王家秀.腹腔镜子宫腺肌瘤病灶切除术治疗子宫腺肌病的临床分析[J].腹腔镜外科杂志,2010,15(9):712-714
[4]梅海炳,汪期明,何忠威,等.子宫动脉栓塞术在子宫腺肌病治疗中的应用[J].现代实用医学,2009,21(5):445-446.
[5]乐杰.妇产科学[M].7版.北京:人民卫生出版社,2011:325.
[6]何文容,易村犍,凌晟荣.改良腹腔镜辅助子宫腺肌瘤剔除术[J].郧阳医学院学报,2010,29(1):64-65.
[7]沈丹,祝育德,肖贤,等.腹腔镜下保守手术与子宫动脉栓塞术治疗子宫腺肌症疗效比较[J].川北医学院学报,2011,26(6):513-517.
[8]柯丽娜,林虹.腹腔镜下子宫腺肌病病灶切除术治疗子宫腺肌病[J].实用妇产科杂志,209,25(4):251-252.
[9]林琪秀,何云芹.左炔诺孕酮宫内节育系统干预对子宫腺肌病血清糖链多肽抗原125水平的影响[J].中国乡村医药,2013,20(8):38-39.
[10]倪金龙,牛铭钢.左炔诺孕酮宫内缓释系统治疗围绝经期功血的研究概况[J].安徽医学,2010,31(1):79-80.
[11]胡亚莉.腹腔镜卵巢囊肿摘除术后应用曼月乐环的疗效研究[J].中国社区医师,2014,30(20):69-70.
[12]成九梅,段华,刘芸,等.腹腔镜下子宫腺肌病灶挖除及子宫动脉阻断治疗子宫腺肌病的长期疗效分析[J].北京医学,2014,36(1):19-23.
[13]宋英.卵巢子宫内膜异位症恶变1例报告[J].中国当代医药,2013,20(32):157-158.
[14]赵惠杰.曼月乐对不愿手术的子宫内膜异位症患者的疗效观察[J].中国当代医药,2014,21(8):177-179.
[15]张彭南,朱杰,薛晓红.腹腔镜下子宫腺肌病病灶切除术治疗子宫腺肌病的临床分析[J].现代妇产科进展,2015,24(2):135-137.