温胆汤治疗慢性充血性心力衰竭临床分析
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摘要
目的探讨温胆汤加减对慢性充血性心力衰竭患者的影响。方法选取慢性充血性心力衰竭患者60例,随机分为治疗组和对照组,每组30例,对照组为常规心衰西医治疗,治疗组加用温胆汤加减,两组用药疗程均为6周。实验前后分别监测心功能分级和BNP。结果治疗后2组心功能明显改善,血BNP均较治疗前均明显下降,治疗后治疗组血BNP下降及心功能的改善均明显高于对照组(P<0.05)。结论常规抗心衰治疗基础上应用温胆汤加减改善慢性充血性心力衰竭方面也有一定效果。
Objective To observe the effects of Wendan decoction on chronic heart failure(CHF)patients with BNP.Methods This study selected60 cases of CHF patients,sixty cases of DHF were randomized into two groups,30 cases in a treatment group and30 cases in a control group.In the control group,the standardized medication of modern western medicine was applied,30 cases of Chinese medicine group were treated with Wendan decoction orally.After 6 weeks,the curative effects of two groups were observed.Results After treatment,BNP level was reduced significantly in the treatment group as compared with the control group,presenting the statistically significant difference(P<0.05).BNP levels distance within group comparisons,the two groups were statistically significant(P<0.05);Chinese medicine group compared to the control group,there was statistically significant difference(P <0.05).Conclusion Wendan decoction can decreased plasma BNP concentration and improved heart function,which had obviously effect in clinical.
Objective To observe the effects of Wendan decoction on chronic heart failure(CHF)patients with BNP.Methods This study selected60 cases of CHF patients,sixty cases of DHF were randomized into two groups,30 cases in a treatment group and30 cases in a control group.In the control group,the standardized medication of modern western medicine was applied,30 cases of Chinese medicine group were treated with Wendan decoction orally.After 6 weeks,the curative effects of two groups were observed.Results After treatment,BNP level was reduced significantly in the treatment group as compared with the control group,presenting the statistically significant difference(P<0.05).BNP levels distance within group comparisons,the two groups were statistically significant(P<0.05);Chinese medicine group compared to the control group,there was statistically significant difference(P <0.05).Conclusion Wendan decoction can decreased plasma BNP concentration and improved heart function,which had obviously effect in clinical.
引文
[1]于浥淳,张新超.急性心力衰竭血液生化标志物临床研究近况[J].中国医药导报,2010,7(27):13-14.
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[6]国家中医药管理局医政司胸痹急病协作组·胸痹心水(冠心病心力衰竭中医急症诊疗规范[J].中国中医急症,1995,4(4):179.
[7]中华医学会心血管病学分会,中华心血管病杂志编辑委员会.慢性收缩性心力衰竭治疗建议[J].中华心血管病杂志,2002,30(1):7-23.
[8]中华人民共和国卫生部.中药新药治疗心力衰竭的临床研究指导原则[S].北京:中国医药科技出版社,2002.
[9]陈炼,朱伟达,楼丽娜,等.BNP对判断心力衰竭严重程度及其预后的价值[J].苏州大学学报(医学版),2006,26(4):110-111.
[10]庞俊忠.临床中药学[M].北京:中国医药科技出版社,1989:369,99.
[2]Dibbs Z,Thomby J,white BG,et al.Natural valiability of circulating levels of cytokines and cytokine receptors in patients with heart failure;implications for clinical trials[J].J Am coll Cardiol,1999,33:1935.
[3]王妍.BNP与心力衰竭诊断的临床进展[J].中外医疗,2009(5):154.
[4]陈灏珠(美).临床心脏病学[M].上海:上海医科大学出版社,1999:233.
[5]张子彬,TsungO.Cheng,张玉传.充血性心力衰竭[M].北京:科学技术文献出版社,2002:212.
[6]国家中医药管理局医政司胸痹急病协作组·胸痹心水(冠心病心力衰竭中医急症诊疗规范[J].中国中医急症,1995,4(4):179.
[7]中华医学会心血管病学分会,中华心血管病杂志编辑委员会.慢性收缩性心力衰竭治疗建议[J].中华心血管病杂志,2002,30(1):7-23.
[8]中华人民共和国卫生部.中药新药治疗心力衰竭的临床研究指导原则[S].北京:中国医药科技出版社,2002.
[9]陈炼,朱伟达,楼丽娜,等.BNP对判断心力衰竭严重程度及其预后的价值[J].苏州大学学报(医学版),2006,26(4):110-111.
[10]庞俊忠.临床中药学[M].北京:中国医药科技出版社,1989:369,99.