皮肤软组织巨细胞瘤1例
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摘要
报告1例右上臂软组织巨细胞瘤青年患者。患者男,25岁,因"右上臂结节3年"于我科就诊。皮肤专科检查:患者右上臂见一直径1 cm大小褐色结节,质韧,边界尚清,表面光滑,无破溃、糜烂。病理检查示:表皮正常。真皮内见一肿瘤组织,肿瘤周边见纤维组织形成的假包膜,内为增生的圆形或卵圆形的单核细胞及破骨巨细胞样的多核巨细胞,细胞无明显异型性,局灶可见含铁血黄素。免疫组化:CD68(+),肌间线蛋白Desmin(-),平滑肌肌动蛋白SMA(-)。结合组织病理学、免疫组化检查,可排除其他良恶性肿瘤,诊断为软组织巨细胞瘤。手术全切除,半年后随访无复发。
引文
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[8] 喻珊,王鹤林,刘磊.睾丸软组织巨细胞瘤临床病理观察[J].临床与实验病理学杂志,2011,27(5):537-538.
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[10] 朱学骏,涂平,陈喜雪,等.皮肤病的组织病理学诊断[M].3版.北京:北京大学医学出版社,2016:503-504.
[11] RIGHI S,BOFFANO P,PATETTA R,et al.Soft tissue giant cell tumor of low malignant potential with 3 localizations:report of a case[J].Oral Surg Oral Med Oral Pathol Oral Radiol,2014,118(5):e135-e138.
[2] GUCCION J G,ENZINGER F M.Malignant giant cell tumor of soft parts.An analysis of 32 cases[J].Cancer,1972,29(6):1518-1529.
[3] HAFIZ S,SHAHEEN M,AWADH N,et al.Giant cell tumor of soft tissue:a case report for the first time in ear[J].Human Pathology:Case Reports,2017,10:12-14.
[4] O′CONNELL J X,WEHRLI B M,NIELSEN G P.Giant cell tumors of soft tissue:a clinicopathologic study of 18 benign and malignant tumors[J].Am J Surg Pathol,2000,24(3):386-395.
[5] OLIVEIRA A M,DEI TOS A P,FLETCHER C D,et al.Primary giant cell tumor of soft tissues:a study of 22 cases [J].Am J Surg Pathol,2000,24(2):248-256.
[6] 杨光华.原发性软组织巨细胞瘤良恶性质的重新评价[J].中华病理学杂志,2001,30(1):10-11.
[7] HOLST V A,ELENITSAS R.Primary gient cell tumor of soft tissue [J].J Cutan Pathol,2001,28(9):492-495.
[8] 喻珊,王鹤林,刘磊.睾丸软组织巨细胞瘤临床病理观察[J].临床与实验病理学杂志,2011,27(5):537-538.
[9] 尚诗瑶,洪楠.多发性软组织巨细胞瘤1例[J].中国医学影像技术,2013,29(9):1550-1551.
[10] 朱学骏,涂平,陈喜雪,等.皮肤病的组织病理学诊断[M].3版.北京:北京大学医学出版社,2016:503-504.
[11] RIGHI S,BOFFANO P,PATETTA R,et al.Soft tissue giant cell tumor of low malignant potential with 3 localizations:report of a case[J].Oral Surg Oral Med Oral Pathol Oral Radiol,2014,118(5):e135-e138.