纳米碳染色定位在结直肠癌手术中应用的研究进展
|
摘要
结直肠癌是全球癌症发病和死亡的重要原因,手术治疗是其主要治疗方式,在术前运用纳米碳对肿瘤和淋巴结进行染色定位,能够减少术中寻找肿瘤时间,提高淋巴结检出数量,对改善手术效果、为患者提供更好的预后具有积极作用。本文对目前纳米炭在结直肠癌手术中的相关应用进行回顾,阐述纳米碳在结直肠癌手术中应用的优缺点及面临的挑战。
Colorectal cancer is an important cause of cancer morbidity and mortality worldwide. Surgical treatment is the main treatment. The use of carbon nanoparticles to stain and locate the tumors and lymph nodes before operation can reduce the time of searching for tumors during operation, increase the number of lymph nodes detected, and play a positive role in improving the effect of surgery and providing better prognosis for patients. This paper reviews the application of nanocarbon in colorectal cancer surgery, and describes the advantages, disadvantages and challenges of nanocarbon in colorectal cancer surgery.
Colorectal cancer is an important cause of cancer morbidity and mortality worldwide. Surgical treatment is the main treatment. The use of carbon nanoparticles to stain and locate the tumors and lymph nodes before operation can reduce the time of searching for tumors during operation, increase the number of lymph nodes detected, and play a positive role in improving the effect of surgery and providing better prognosis for patients. This paper reviews the application of nanocarbon in colorectal cancer surgery, and describes the advantages, disadvantages and challenges of nanocarbon in colorectal cancer surgery.
引文
[1] Connell LC,Mota JM,Braghiroli MI,et al. The Rising Incidence of Younger Patients With Colorectal Cancer:Questions About Screening,Biology,and Treatment[J].Curr Treat Options Oncol,2017,18(4):23.
[2] Siegel RL,Miller KD,Fedewa SA,et al. Colorectal cancer statistics,2017[J]. CA Cancer J Clin,2017,67(3):177-193.
[3] Chen W,Zheng R,Baade P D,et al. Cancer statistics in China,2015[J]. CA Cancer J Clin,2016,66(2):115-132.
[4] National Comprehensive Cancer Network. Clinical Practice Guidelines in Oncology[N]. Uterine Neoplasms,June 7,2017.
[5] Pedziwiatr M,Malczak P,Mizera M,et al. There is no difference in outcome between laparoscopic and open surgery for rectal cancer:a systematic review and meta-analysis on short-and long-term oncologic outcomes[J]. Tech Coloproctol,2017,21(8):595-604.
[6] Fu KI,Fujii T,Kato S,et al. A new endoscopic tattooing technique for identifying the location of colonic lesions during laparoscopic surgery:a comparison with the conventional technique[J]. Endoscopy,2001,33(8):687-691.
[7] Yeung JM,Maxwell-Armstrong C,Acheson AG. Colonic tattooing in laparoscopic surgery-making the mark?[J]. Colorectal Dis,2009,11(5):527-530.
[8] Elarini T,Wexner SD,Isenberg GA. The need for standardization of colonoscopic tattooing of colonic lesions[J].Dis Colon Rectum,2015,58(2):264-267.
[9] Cho YB,Lee WY,Yun HR,et al. Tumor localization for laparoscopic colorectal surgery[J]. World J Surg,2007,31(7):1491-1495.
[10] Kethu SR,Banerjee S,Desilets D,et al. Endoscopic tattooing[J]. Gastrointest Endosc,2010,72(4):681-685.
[11] Askin MP,Waye JD,Fiedler L,et al. Tattoo of colonic neoplasms in 113 patients with a new sterile carbon compound[J]. Gastrointest Endosc,2002,56(3):339-342.
[12] Yan J,Xue F,Chen H,et al. A multi-center study of using carbon nanoparticles to track lymph node metastasis in T1-2 colorectal cancer[J]. Surg Endosc,2014,28(12):3315-3321.
[13] Arteaga-Gonzalez I,Martin-Malagon A,Fernandez EM,et al. The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors:a prospective comparative clinical study[J]. World J Surg,2006,30(4):605-611.
[14] Wexner SD,Cohen SM,Ulrich A,et al. Laparoscopic colorectal surgery—are we being honest with our patients?[J].Dis Colon Rectum,1995,38(7):723-727.
[15]林晨,张再重,王烈,等.纳米碳染色标记在内镜下切除早期结肠癌后追加外科手术中的病灶定位作用[J].中华胃肠外科杂志,2017,20(8):910-913.
[16] Mcarthur CS,Roayaie S,Waye JD. Safety of preoperation endoscopic tattoo with india ink for identification of colonic lesions[J]. Surg Endosc,1999,13(4):397-400.
[17] Feingold DL,Addona T,Forde KA,et al. Safety and reliability of tattooing colorectal neoplasms prior to laparoscopic resection[J]. J Gastrointest Surg,2004,8(5):543-546.
[18] Park JW,Sohn DK,Hong CW,et al. The usefulness of preoperative colonoscopic tattooing using a saline test injection method with prepackaged sterile India ink for localization in laparoscopic colorectal surgery[J]. Surg Endosc,2008,22(2):501-505.
[19] Wang Q,Chen E,Cai Y,et al. Preoperative endoscopic localization of colorectal cancer and tracing lymph nodes by using carbon nanoparticles in laparoscopy[J]. World J Surg Oncol,2016,14(1):231.
[20] Wang Y,Deng H,Chen H,et al. Preoperative Submucosal Injection of Carbon Nanoparticles Improves Lymph Node Staging Accuracy in Rectal Cancer after Neoadjuvant Chemoradiotherapy[J]. J Am Coll Surg,2015,221(5):923-930.
[21]张相春,王延磊,晏伟,等.纳米碳淋巴示踪剂在腹腔镜结直肠癌手术中的应用探讨[J].中华医学杂志,2015,95(32):2612-2615.
[22] Cai HK,He HF,Tian W,et al. Colorectal cancer lymph node staining by activated carbon nanoparticles suspension in vivo or methylene blue in vitro[J]. World J Gastroenterol,2012,18(42):6148-6154.
[23]杨斌,李英儒,温润龙,等.纳米碳淋巴示踪技术应用于腹腔镜结直肠癌根治术的意义[J].中华胃肠外科杂志,2015,(6):549-552.
[24] Zhang XM,Liang JW,Wang Z,et al. Effect of preoperative injection of carbon nanoparticle suspension on the outcomes of selected patients with mid-low rectal cancer[J].Chin J Cancer,2016,35:33.
[25] Dawson K,Wiebusch A,Thirlby RC. Preoperative tattooing and improved lymph node retrieval rates from colectomy specimens in patients with colorectal cancers[J].Arch Surg,2010,145(9):826-830.
[26] Herrera-Ornelas L,Justiniano J,Castillo N,et al. Metastases in small lymph nodes from colon cancer[J]. Arch Surg,1987,122(11):1253-1256.
[27] Gartland KP,Eason CT,Bonner FW,et al. Effects of biliary cannulation and buthionine sulphoximine pretreatment on the nephrotoxicity of para-aminophenol in the Fischer 344 rat[J]. Arch Toxicol,1990,64(1):14-25.
[28] Yang M,Pepe D,Schlachta C M,et al. Endoscopic tattoo:the importance and need for standardised guidelines and protocol[J]. J R Soc Med,2017,110(7):287-291.
[29] Joshi P,Kaya C,Surana S,et al. A novel method in decision making for the diagnosis of anterior urethral stricture:using methylene blue dye[J]. Turk J Urol,2017,43(4):502-506.
[30] Chan BS,Becker T,Chiew AL,et al. Vasoplegic Shock Treated with Methylene Blue Complicated by Severe Serotonin Syndrome[J]. J Med Toxicol,2018,14(1):100-103.
[31] Tay JH,Wallbridge PD,Larobina M,et al. Electromagnetic Navigation Bronchoscopy-directed Pleural Tattoo to Aid Surgical Resection of Peripheral Pulmonary Lesions[J].J Bronchology Interv Pulmonol,2016,23(3):245-250.
[32] Chu JN,Lazar J,Badger J. A postoperative blue rash:indigo carmine dye extravasation[J]. Int J Dermatol,2015,54(9):e371-e372.
[33] Takahashi H,Zaidi N,Berber E. An initial report on the intraoperative use of indocyanine green fluorescence imaging in the surgical management of liver tumorss[J].J Surg Oncol,2016,114(5):625-629.
[34] Zhai Q,Wang Y,Tian A. Severe hemodynamic instability after indocyanine green injection during off-pump coronary artery bypass grafting:A case report[J]. Medicine(Baltimore),2017,96(46):e8766.
[35] Hammond DC,Lane FR,Welk RA,et al. Endoscopic tattooing of the colon. An experimental study[J]. Am Surg,1989,55(7):457-461.
[36] Reynolds IS,Majeed MH,Soric I,et al. Endoscopic tattooing to aid tumour localisation in colon cancer:the need for standardisation[J]. Ir J Med Sci,2017,186(1):75-80.
[37] Puccio F,Solazzo M,Marciano P,et al. Laparoscopic resection of calcifying fibrous pseudotumor of the gastric wall. A unique case report[J]. Surg Endosc,2001,15(10):1227.
[38] Wang H,Yang ST,Cao A,et al. Quantification of carbon nanomaterials in vivo[J]. Acc Chem Res,2013,46(3):750-760.
[39] Pardo J,Peng Z,Leblanc RM. Cancer Targeting and Drug Delivery Using Carbon-Based Quantum Dots and Nanotubes[J]. Molecules,2018,23(2):378.
[40] Xie P,Yang ST,He T,et al. Bioaccumulation and Toxicity of Carbon Nanoparticles Suspension Injection in Intravenously Exposed Mice[J]. Int J Mol Sci,2017,18(12):2562.
[2] Siegel RL,Miller KD,Fedewa SA,et al. Colorectal cancer statistics,2017[J]. CA Cancer J Clin,2017,67(3):177-193.
[3] Chen W,Zheng R,Baade P D,et al. Cancer statistics in China,2015[J]. CA Cancer J Clin,2016,66(2):115-132.
[4] National Comprehensive Cancer Network. Clinical Practice Guidelines in Oncology[N]. Uterine Neoplasms,June 7,2017.
[5] Pedziwiatr M,Malczak P,Mizera M,et al. There is no difference in outcome between laparoscopic and open surgery for rectal cancer:a systematic review and meta-analysis on short-and long-term oncologic outcomes[J]. Tech Coloproctol,2017,21(8):595-604.
[6] Fu KI,Fujii T,Kato S,et al. A new endoscopic tattooing technique for identifying the location of colonic lesions during laparoscopic surgery:a comparison with the conventional technique[J]. Endoscopy,2001,33(8):687-691.
[7] Yeung JM,Maxwell-Armstrong C,Acheson AG. Colonic tattooing in laparoscopic surgery-making the mark?[J]. Colorectal Dis,2009,11(5):527-530.
[8] Elarini T,Wexner SD,Isenberg GA. The need for standardization of colonoscopic tattooing of colonic lesions[J].Dis Colon Rectum,2015,58(2):264-267.
[9] Cho YB,Lee WY,Yun HR,et al. Tumor localization for laparoscopic colorectal surgery[J]. World J Surg,2007,31(7):1491-1495.
[10] Kethu SR,Banerjee S,Desilets D,et al. Endoscopic tattooing[J]. Gastrointest Endosc,2010,72(4):681-685.
[11] Askin MP,Waye JD,Fiedler L,et al. Tattoo of colonic neoplasms in 113 patients with a new sterile carbon compound[J]. Gastrointest Endosc,2002,56(3):339-342.
[12] Yan J,Xue F,Chen H,et al. A multi-center study of using carbon nanoparticles to track lymph node metastasis in T1-2 colorectal cancer[J]. Surg Endosc,2014,28(12):3315-3321.
[13] Arteaga-Gonzalez I,Martin-Malagon A,Fernandez EM,et al. The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors:a prospective comparative clinical study[J]. World J Surg,2006,30(4):605-611.
[14] Wexner SD,Cohen SM,Ulrich A,et al. Laparoscopic colorectal surgery—are we being honest with our patients?[J].Dis Colon Rectum,1995,38(7):723-727.
[15]林晨,张再重,王烈,等.纳米碳染色标记在内镜下切除早期结肠癌后追加外科手术中的病灶定位作用[J].中华胃肠外科杂志,2017,20(8):910-913.
[16] Mcarthur CS,Roayaie S,Waye JD. Safety of preoperation endoscopic tattoo with india ink for identification of colonic lesions[J]. Surg Endosc,1999,13(4):397-400.
[17] Feingold DL,Addona T,Forde KA,et al. Safety and reliability of tattooing colorectal neoplasms prior to laparoscopic resection[J]. J Gastrointest Surg,2004,8(5):543-546.
[18] Park JW,Sohn DK,Hong CW,et al. The usefulness of preoperative colonoscopic tattooing using a saline test injection method with prepackaged sterile India ink for localization in laparoscopic colorectal surgery[J]. Surg Endosc,2008,22(2):501-505.
[19] Wang Q,Chen E,Cai Y,et al. Preoperative endoscopic localization of colorectal cancer and tracing lymph nodes by using carbon nanoparticles in laparoscopy[J]. World J Surg Oncol,2016,14(1):231.
[20] Wang Y,Deng H,Chen H,et al. Preoperative Submucosal Injection of Carbon Nanoparticles Improves Lymph Node Staging Accuracy in Rectal Cancer after Neoadjuvant Chemoradiotherapy[J]. J Am Coll Surg,2015,221(5):923-930.
[21]张相春,王延磊,晏伟,等.纳米碳淋巴示踪剂在腹腔镜结直肠癌手术中的应用探讨[J].中华医学杂志,2015,95(32):2612-2615.
[22] Cai HK,He HF,Tian W,et al. Colorectal cancer lymph node staining by activated carbon nanoparticles suspension in vivo or methylene blue in vitro[J]. World J Gastroenterol,2012,18(42):6148-6154.
[23]杨斌,李英儒,温润龙,等.纳米碳淋巴示踪技术应用于腹腔镜结直肠癌根治术的意义[J].中华胃肠外科杂志,2015,(6):549-552.
[24] Zhang XM,Liang JW,Wang Z,et al. Effect of preoperative injection of carbon nanoparticle suspension on the outcomes of selected patients with mid-low rectal cancer[J].Chin J Cancer,2016,35:33.
[25] Dawson K,Wiebusch A,Thirlby RC. Preoperative tattooing and improved lymph node retrieval rates from colectomy specimens in patients with colorectal cancers[J].Arch Surg,2010,145(9):826-830.
[26] Herrera-Ornelas L,Justiniano J,Castillo N,et al. Metastases in small lymph nodes from colon cancer[J]. Arch Surg,1987,122(11):1253-1256.
[27] Gartland KP,Eason CT,Bonner FW,et al. Effects of biliary cannulation and buthionine sulphoximine pretreatment on the nephrotoxicity of para-aminophenol in the Fischer 344 rat[J]. Arch Toxicol,1990,64(1):14-25.
[28] Yang M,Pepe D,Schlachta C M,et al. Endoscopic tattoo:the importance and need for standardised guidelines and protocol[J]. J R Soc Med,2017,110(7):287-291.
[29] Joshi P,Kaya C,Surana S,et al. A novel method in decision making for the diagnosis of anterior urethral stricture:using methylene blue dye[J]. Turk J Urol,2017,43(4):502-506.
[30] Chan BS,Becker T,Chiew AL,et al. Vasoplegic Shock Treated with Methylene Blue Complicated by Severe Serotonin Syndrome[J]. J Med Toxicol,2018,14(1):100-103.
[31] Tay JH,Wallbridge PD,Larobina M,et al. Electromagnetic Navigation Bronchoscopy-directed Pleural Tattoo to Aid Surgical Resection of Peripheral Pulmonary Lesions[J].J Bronchology Interv Pulmonol,2016,23(3):245-250.
[32] Chu JN,Lazar J,Badger J. A postoperative blue rash:indigo carmine dye extravasation[J]. Int J Dermatol,2015,54(9):e371-e372.
[33] Takahashi H,Zaidi N,Berber E. An initial report on the intraoperative use of indocyanine green fluorescence imaging in the surgical management of liver tumorss[J].J Surg Oncol,2016,114(5):625-629.
[34] Zhai Q,Wang Y,Tian A. Severe hemodynamic instability after indocyanine green injection during off-pump coronary artery bypass grafting:A case report[J]. Medicine(Baltimore),2017,96(46):e8766.
[35] Hammond DC,Lane FR,Welk RA,et al. Endoscopic tattooing of the colon. An experimental study[J]. Am Surg,1989,55(7):457-461.
[36] Reynolds IS,Majeed MH,Soric I,et al. Endoscopic tattooing to aid tumour localisation in colon cancer:the need for standardisation[J]. Ir J Med Sci,2017,186(1):75-80.
[37] Puccio F,Solazzo M,Marciano P,et al. Laparoscopic resection of calcifying fibrous pseudotumor of the gastric wall. A unique case report[J]. Surg Endosc,2001,15(10):1227.
[38] Wang H,Yang ST,Cao A,et al. Quantification of carbon nanomaterials in vivo[J]. Acc Chem Res,2013,46(3):750-760.
[39] Pardo J,Peng Z,Leblanc RM. Cancer Targeting and Drug Delivery Using Carbon-Based Quantum Dots and Nanotubes[J]. Molecules,2018,23(2):378.
[40] Xie P,Yang ST,He T,et al. Bioaccumulation and Toxicity of Carbon Nanoparticles Suspension Injection in Intravenously Exposed Mice[J]. Int J Mol Sci,2017,18(12):2562.